Human Anti-TPO Recombinant Antibody (clone TF3.5) (CAT#: FAMAB-0036JF)
Autoantibody
Recombinant monoclonal antibody can specifically bind TPO outside the immunodominant region. This human anti-non-IDR antibody TF3.5 can be potentially used in the treatment of patients with TPO autoantibody-positive Graves.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Thyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7987/21449_B_2_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7987/21449_B_2_5.jpg
Figure 2 RNA cell line category: Group enriched (Karpas-707, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115705-TPO/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115705-TPO/subcellular
Specifications
- Host Species
- Human
- Derivation
- Human phage display Fab library
- Type
- Human IgG
- Specificity
- Human non-IDR TPO
- Species Reactivity
- Human
- Clone
- TF3.5
- Applications
- WB, ELISA, FC
- Related Disease
- TPO autoantibody-positive Graves
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The TPO antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Flow Cytometry.
Target
Related Resources
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-999-F(E) | Recombinant Human Anti-TPO Antibody Fab Fragment | IP, IF, FuncS | Fab |
| PFBW-123 | Human Anti-TPO Recombinant Antibody (clone TR1.9); Fab Fragment | WB, ELISA | Human Fab |
| FAMAB-0013JF-F(E) | Human Anti-TPO Recombinant Antibody (clone A12); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0014JF-F(E) | Human Anti-TPO Recombinant Antibody (clone B8); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0015JF-F(E) | Human Anti-TPO Recombinant Antibody (clone T5); Fab Fragment | WB, ELISA, FuncS | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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