Human Anti-TPO Recombinant Antibody (clone T5)
CAT#: FAMAB-0015JF
Recombinant monoclonal antibody specially binds to VI/VIII of human TPO. This human anti-TPO antibody T5 can be widely used in the treatment of Graves' disease.
Gene Expression
Normal Tissue
Figure 1 Thyroid gland
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7987/21449_B_2_5.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (Karpas-707, RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115705-TPO/subcellular
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Specifications
- Host Species
- Human
- Derivation
- Human phage display scFv library
- Type
- Human IgG
- Specificity
- Human TPO
- Species Reactivity
- Human
- Clone
- T5
- Applications
- WB, ELISA, IHC, FC
- Related Disease
- Graves' disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The TPO antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Flow Cytometry.
Target
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Highly Effective for Research
The Human Anti-TPO Recombinant Antibody has been a highly effective tool in our lab's thyroid research. Its specificity and sensitivity are unmatched, allowing us to accurately measure TPO in a variety of assays. We particularly appreciate its flexibility in ELISA and Western Blot, enabling us to study TPO's role in different physiological contexts.
Versatile and Consistent Performance
Employing this antibody in our research has shown us its versatile application in both Western Blot and ELISA. The consistent performance it delivers has been vital in expanding our insights into TPO's mechanism and its implications in thyroid function. We highly recommend it for anyone researching thyroid-related proteins.
Q&As
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What are the primary applications for the Human Anti-TPO Recombinant Antibody (clone T5)?
A: This antibody is utilized chiefly in Western Blot (WB), Enzyme-linked Immunosorbent Assay (ELISA), Immunohistochemistry (IHC), and Flow Cytometry (FC) applications. Its versatility makes it valuable for detecting Thyroid Peroxidase (TPO), particularly in research focused on thyroid function and autoimmune thyroid disorders like Graves' disease.
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Can this antibody be modified or conjugated for specific research needs?
A: While the default form is unconjugated, various conjugation options like PE, APC, Biotin, FITC, and others are available. This flexibility allows researchers to tailor the antibody for specific assay requirements and detection methods.
View the frequently asked questions answered by Creative Biolabs Support.
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Related Diseases
Autoimmune Thyroid Disease
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Clone T5"
- CAT
- Product Name
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Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-999 | Recombinant Human Anti-TPO Antibody | WB, ELISA, IHC, FuncS | IgG |
| HPAB-2017-FY | Human Anti-TPO Recombinant Antibody (clone FY-019) | ELISA | Human IgG |
| FAMAB-0036JF | Human Anti-TPO Recombinant Antibody (clone TF3.5) | WB, ELISA, FC | Human IgG |
| FAMAB-0042JF | Human Anti-TPO Recombinant Antibody (clone ICA5) | WB, ELISA, FuncS | Human IgG |
| VS3-FY1477 | Recombinant Mouse Anti-TPO Antibody (clone 9G3-6F3-9B7) | IHC-P | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-999-F(E) | Recombinant Human Anti-TPO Antibody Fab Fragment | IP, IF, FuncS | Fab |
| HPAB-2017-FY-F(E) | Human Anti-TPO Recombinant Antibody (clone FY-019); Fab Fragment | ELISA | Human Fab |
| FAMAB-0013JF-F(E) | Human Anti-TPO Recombinant Antibody (clone A12); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0036JF-F(E) | Human Anti-TPO Recombinant Antibody (clone TF3.5); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0042JF-F(E) | Human Anti-TPO Recombinant Antibody (clone ICA5); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBW-123 | Human Anti-TPO Recombinant Antibody (clone TR1.9); scFv Fragment | WB, ELISA | Human scFv |
| HPAB-2017-FY-S(P) | Human Anti-TPO Recombinant Antibody (clone FY-019); scFv Fragment | ELISA | Human scFv |
| FAMAB-0013JF-S(P) | Human Anti-TPO Recombinant Antibody (clone A12); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| FAMAB-0036JF-S(P) | Human Anti-TPO Recombinant Antibody (clone TF3.5); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| FAMAB-0042JF-S(P) | Human Anti-TPO Recombinant Antibody (clone ICA5); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2215CQ | Mouse Anti-TPO Recombinant Antibody (clone CBL296) | Neut, ELISA | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3658 | Rabbit Anti-TPO Recombinant Antibody (clone DS3658AB) | IHC-P, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4548 | PE-DQB1*03:02/Human TPO (IDVWLGGLAENFLP) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1124-YJ3 | Human Anti-TPO Recombinant Autoantibody (clone DN4) | ELISA, FuncS | Human IgG1 kappa |
| VS-1124-YJ4 | Human Anti-TPO Recombinant Autoantibody (clone TR1.41) | ELISA | Human IgG1 lambda |
| VS-1124-YJ14 | Human Anti-TPO Recombinant Autoantibody (clone RII-9) | ELISA | Human IgG1 |
| VS-1124-YJ15 | Human Anti-TPO Recombinant Autoantibody (clone RI-8) | ELISA | Human IgG1 |
| VS-1124-YJ16 | Human Anti-TPO Recombinant Autoantibody (clone RI-33) | ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC757 | Recombinant Anti-TPO Vesicular Antibody, EV Displayed (VS-0425-YC757) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7469 | Anti-TPO Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC188 | Recombinant Anti-TPO (Domain VI x Domain VIII) Biparatopic Antibody, Tandem scFv (Clone B8 x Clone A12) | ELISA, IHC, WB | Tandem scFv |
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