DRB1*04:01/Human GAD2 (IAFTSEHSHFSLK) MHC Tetramer
CAT#: MHC-CN0700
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78177/163309_B_9_5.jpg
Normal Tissue
Figure 2 Pancreas
Pancreatic endocrine cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78177/163309_A_3_3.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (SCLC-21H)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136750-GAD2
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Specifications
- Allele
- DRB1*04:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- GAD2
- Antigen Species
- Human
- Peptide
- IAFTSEHSHFSLK
- Conjugate
- Unconjugated
- Application
- FCM, IHC
Target
- Antigen Introduction
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
- Alternative Names
- GAD65
- Gene ID
- 2572
- UniProt ID
- Q05329
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Related Diseases
Maturity Onset Diabetes of the Young
Downloadable Resources
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Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "GAD2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2430MZ | Recombinant Mouse Anti-Rat GAD2 Antibody (clone HBE-7) | IHC-FoFr, IHC-Fr, IHC-P, WB | Mouse antibody |
| HPAB-1982-FY | Human Anti-GAD2 Recombinant Antibody (clone b78) | Inhib | Human IgG1, λ |
| VS1-YJ63 | Mouse Anti-GAD2 Recombinant Antibody (clone 144) | WB, FC, IP | Mouse IgG1 |
| VS3-QX454 | Mouse Anti-GAD2 Recombinant Antibody (clone 6D5-E8-E4) | WB | Mouse IgG2b |
| VS3-QX455 | Mouse Anti-GAD2 Recombinant Antibody (clone 458CT17.2.4) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1389 | Hi-Affi™ Rabbit Anti-GAD2 Recombinant Antibody (clone DS1389AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1982-FY-F(E) | Human Anti-GAD2 Recombinant Antibody (clone b78); Fab Fragment | Inhib | Human Fab, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1982-FY-S(P) | Human Anti-GAD2 Recombinant Antibody (clone b78); scFv Fragment | Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF030 | DRB1*04:01/Human GAD65 (IAFTSEHSHFSLK) MHC Monomer | MHC Multimer | |
| MHC-YF033 | DRB1*04:01/Human GAD65 (NFIRMVISNPAAT) MHC Monomer | MHC Multimer | |
| MHC-YF034 | DRB1*04:01/Human GAD65 (DVMNILLQYVVKSFDRSTKV) MHC Monomer | MHC Multimer | |
| MHC-YF035 | DRB1*04:01/Human GAD65 (KGMAALPRLIAFTSEHSHFS) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC793 | AbPlus™ Anti-GAD2 Magnetic Beads (VS-0724-YC793) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2716 | Anti-GAD2 Immunohistochemistry Kit | IHC |
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