Recombinant Human Anti-INS Soluble TCR (C-Cys) (VS-0622-YF4562)
CAT#: VS-0622-YF4562
Human TCR recognizes INS peptide (MLYQHLLPL + OX(M1)) in the context of HLA-A*02:01. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
Gene Expression
Normal Tissue
Figure 1 Pancreas
Pancreatic endocrine cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4932/115849_A_1_3.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (EFO-21, U-2 OS, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000254647-INS
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Specifications
- Host Species
- Human
- Target
- INS
- Species Reactivity
- Human
- Epitope
- MLYQHLLPL + OX(M1)
- MHC
- HLA-A*02:01
- Type
- Soluble TCR (C-Cys)
- Related Disease
- Type 1 diabetes (T1D)
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
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Related Diseases
Maturity Onset Diabetes of the Young
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Datasheet
MSDS
COA
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|---|---|---|---|
| NAB-1554-VHH | Recombinant Anti-human INS VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
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| DrMAB-1026 | Mouse Anti-INS Recombinant Antibody (clone YC182); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0182-YC-F(E) | Mouse Anti-INS Recombinant Antibody (clone 123); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0183-YC-F(E) | Mouse Anti-INS Recombinant Antibody (clone 124); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0184-YC-F(E) | Mouse Anti-INS Recombinant Antibody (clone 133); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0185-YC-F(E) | Mouse Anti-INS Recombinant Antibody (clone 125); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0152MZ | Recombinant Mouse Anti-Insulin/Proinsulin Antibody (clone E7C5) | ELISA, IHC-Fr | Mouse antibody |
| MRO-1977-CN | Rabbit Anti-INS Polyclonal Antibody (MRO-1977-CN) | IHC, FC, ELISA | Rabbit IgG |
| MOB-0058F | Mouse Anti-INS Recombinant Antibody (MOB-0058F) | IHC-P, IF | Mouse IgG |
| MOB-0059F | Mouse Anti-INS Recombinant Antibody (MOB-0059F) | IHC-P, IF | Mouse IgG |
| VS3-CJ254 | Mouse Anti-INS Recombinant Antibody (clone ABT-INS) | IHC-P | Mouse IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1841 | Rabbit Anti-INS Recombinant Antibody (clone DS1841AB) | IHC-P, WB | Rabbit IgG |
| MOR-4627 | Rabbit Anti-INS Recombinant Antibody (clone TH140DS) | IF, ICC, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0182-YC-S(P) | Mouse Anti-INS Recombinant Antibody (clone 123); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0183-YC-S(P) | Mouse Anti-INS Recombinant Antibody (clone 124); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0184-YC-S(P) | Mouse Anti-INS Recombinant Antibody (clone 133); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0185-YC-S(P) | Mouse Anti-INS Recombinant Antibody (clone 125); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0186-YC-S(P) | Mouse Anti-INS Recombinant Antibody (clone 127); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF029 | DRB1*04:01/Human Proinsulin (GAGSLQPLALEGSLQKRG) MHC Monomer | MHC Multimer | |
| MHC-YF032 | DRB1*04:01/Human Proinsulin (GIVEQCCTSICSLYQ) MHC Monomer | MHC Multimer | |
| MHC-YF236 | A*02:01/Human Ins B. 10 (HLVEALYLV) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3566 | Anti-INS Immunohistochemistry Kit | IHC | |
| VS-0525-XY3567 | Anti-Mouse INS Immunohistochemistry Kit | IHC | |
| VS-0525-XY3568 | Anti-Rat INS Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC112 | Recombinant Anti-INS (α chain x β chain) Biparatopic Antibody, Tandem scFv (Clone AE9D6 x Clone CB5) | ELISA | Tandem scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC195 | Recombinant Anti-INS Eliminating Antibody, pH-Sensitive (5ins16 var.) | Antigen-Sweeping In Vivo. | Human IgG |
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