Mouse Anti-RET Recombinant Antibody (clone 6E4C4) (CAT#: VS3-XY1368)
Clone 6E4C4 is a mouse antibody, which reacts with RET protein. This antibody is suitable for RET detection by ELISA, WB assays.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane, cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8356/1081_D1_2_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane, cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8356/1081_D1_2_selected.jpg
Figure 2 IHC staining of human parathyroid gland
(Immunohistochemical staining of human parathyroid gland shows strong positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_3_8_selected.jpg
(Immunohistochemical staining of human parathyroid gland shows strong positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_3_8_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_B_8_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_B_8_5.jpg
Figure 4 Parathyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_3_8.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_3_8.jpg
Figure 5 Testis
(Cells in seminiferous ducts
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_4_6.jpg
(Cells in seminiferous ducts
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_4_6.jpg
Figure 6 Lymph node
(Germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_7_8.jpg
(Germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_7_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (MCF7, NB-4, SH-SY5Y, THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000165731-RET/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000165731-RET/subcellular
Specifications
- Immunogen
- Recombinant fragment of RET (a.a. 896-1063) expressed in E. coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- RET
- Species Reactivity
- Human
- Clone
- 6E4C4
- Applications
- Enzyme-linked Immunosorbent Assay, Western Blot
Product Property
- Format
- Liquid
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody is recommended for Western Blot (1/500-1/2000) and Enzyme-linked Immunosorbent Assay (1/10000).
Target
- Alternative Names
- Ret Proto-Oncogene; Cadherin-Related Family Member 16; Rearranged During Transfection; RET Receptor Tyrosine Kinase; Cadherin Family Member 12; Proto-Oncogene C-Ret; EC 2.7.10.1; CDHF12; CDHR16; PTC; Ret Proto-Oncogene (Multiple Endocrine Neoplasia And Medullary Thyroid Carcinoma 1, Hirschsprung Disease)
- Gene ID
- 5979
- UniProt ID
- P07949
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "RET"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-844 | Recombinant Anti-RET Antibody | ELISA, IP, FuncS | IgG |
| MOB-1794CT | Recombinant Mouse anti-Human RET Monoclonal antibody (NN0630-20G23) | WB | |
| MRO-1331-CN | Recombinant Rabbit Anti-RET Monoclonal Antibody (CBACN-481) | WB, IF, IHC, IP, FC | Rabbit IgG |
| ZG-065R | Mouse Anti-RET Recombinant Antibody (ZG-065R) | WB, ELISA | Mouse IgG |
| ZG-066R | Mouse Anti-RET Recombinant Antibody (ZG-066R) | WB, ELISA | Mouse IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-844-F(E) | Recombinant Anti-RET Antibody Fab Fragment | RIA, WB, FuncS | Fab |
| MHH-844-F(E) | Recombinant Human Anti-RET Antibody Fab Fragment | ELISA, WB, FC, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-844-S(P) | Recombinant Anti-RET Antibody scFv Fragment | FC, Neut, Funcs | scFv |
| MHH-844-S(P) | Recombinant Human Anti-RET Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-066MZ | Anti-Human RET Recombinant Antibody (Y078) | Cyt, IHC, FC | Human antibody |
| TAB-066MZ-S(P) | Anti-Human RET Recombinant Antibody scFv Fragment (Y078) | IHC | Human antibody |
| TAB-066MZ-F(E) | Anti-Human RET Recombinant Antibody Fab Fragment (Y078) | IHC | Human antibody |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-1148MZ | Chicken Anti-Human RET Polyclonal IgY | WB, ICC | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3052 | Hi-Affi™ Recombinant Rabbit Anti-RET Monoclonal Antibody (DS3052AB) | WB, IHC, ICC, IP, FC | IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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