Recombinant Anti-BSG Vesicular Antibody, EV Displayed (VS-0425-YC238)

CAT#: VS-0425-YC238

The Recombinant Anti-BSG Vesicular Antibody, EV Displayed (VS-0425-YC238) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to BSG-expressed cells or tissues. The BSG is a plasma membrane protein essential in processes like tumor progression. It belongs to the immunoglobulin superfamily.

Gene Expression
Figure 1 IF staining of human cell line HEK 293 Figure 2 Testis Figure 3 Heart muscle Figure 4 Cerebral cortex Figure 5 Colon Figure 6 Kidney Figure 7 RNA cell line category: Low cell line specificity

Recombinant Antibody

  • Application
  • ELISA, FC, Neut, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • BSG
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Basigin (Ok blood group)
  • Biological Process
  • Angiogenesis, Host-virus interaction
  • Molecular Function
  • Blood group antigen, Host cell receptor for virus entry, Receptor
  • Cellular Localization
  • Vesicles, Mid piece, Principal piece, End piece
  • Introduction
  • The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CD147, EMMPRIN, EMPRIN, OK
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