This antibody specifically binding to CD147 results in the killing of T-cells, B-cells, and/or monocytes. So it can also be used in the treatment of graft versus host disease (GVHD), organ transplant rejection diseases (including, without limitation, renal transplant, ocular transplant, and others), cancers (including, without limitation, cancers of the blood (i.e., leukemias and lymphomas), pancreatic, and others), autoimmune diseases, inflammatory diseases, and others.
Figure 1 A graph comparing the activity of the ABX-CBL antibody and the 2.6.1 antibody (also referred to as cem 2.6) in inhibiting the MLR assay. The data demonstrate that the 2.6.1 antibody is not an effective inhibitor.
Figure 2 A comparison of the activity of the ABX-CBL antibody and the 2.6.1 multimeric IgM antibody (also known as ABX-Rb2) in inhibiting the MLR assay, demonstrating that the 2.6.1 multimeric IgM antibody is effective in inhibition of MLR.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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