Afuco™ Anti-BSG ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-156)

Name: Afuco™ Anti-BSG ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-156)
SKU: AFC-TAB-156
Rating: 5 (1 reviews)

CAT#: AFC-TAB-156

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD147. It is a mouse monoclonal antibody intended for use as an immunosuppressive biologic treatment of glucocorticoid-resistant graft versus host disease. It binds to the antigen CD147. It proved slightly less effective than standard antithymocyte globulin therapy.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HEK 293

Immunofluorescent staining of human cell line HEK 293 shows localization to vesicles.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/74870/1466_A2_3_selected.jpg

Normal Tissue Figure 2 Testis

Sertoli cells Staining: High Intensity: Strong Quantity:>75%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_4_6.jpg

Normal Tissue Figure 3 Heart muscle

Cardiomyocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_B_6_6.jpg

Normal Tissue Figure 4 Cerebral cortex

Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_B_7_5.jpg

Normal Tissue Figure 5 Colon

Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_7_3.jpg

Normal Tissue Figure 6 Kidney

Collecting ducts Staining: Medium Intensity: Strong Quantity: <25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_7_5.jpg

RNA Expression Figure 7 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172270-BSG

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Specifications

Host Species
Mouse

Derivation
Mouse

Type
ADCC enhanced antibody

Species Reactivity
Human

Applications
FuncS, IF, Neut, ELISA, FC, IP

Conjugate
Unconjugated

Generic Name
Gavilimomab

Related Disease
Allograft rejection

Product Property

Purity
>95% by SDS-PAGE

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
BSG; basigin (Ok blood group); basigin (OK blood group), OK; basigin; CD147; EMMPRIN; CD147 antigen; OK blood group antigen; collagenase stimulatory factor; leukocyte activation antigen M6;

Gene ID
682

UniProt ID
P35613

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - AFC-TAB-156.pdf

MSDS

MSDS - AFC-TAB-156.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "Gavilimomab"

DrugMonitor™ Anti-Gavilimomab Antibody (VS-1224-YC512)
Gavilimomab is a murine IgM monoclonal antibody (MoAb) developed as a potential treatment for graft-versus-host disease (GvHD). The DrugMonitor™ Anti-Gavilimomab Antibody (VS-1224-YC512) is an anti-drug antibody (ADA) against Gavilimomab. This drug-based antibody is raised in mice immunized with the Gavilimomab. The anti-Gavilimomab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Gavilimomab in samples.

See other products for "BSG"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
IAB-B050(A)	Recombinant Anti-human BSG Intrabody [(D-Arg)₉]	WB, ICC, Neut, FuncS	scFv-(D-Arg)₉
IAB-B050(G)	Recombinant Anti-human BSG Intrabody [+36 GFP]	IF, FC, FuncS	scFv-(+36GFP)
IAB-B050(T)	Recombinant Anti-human BSG Intrabody [Tat]	WB, ICC, FuncS	scFv-Tat

CAT	Product Name	Application	Type
TAB-156	Anti-Human CD147 Recombinant Antibody (TAB-156)	FuncS, IF, Neut, ELISA, FC, IP, ICC	IgM

CAT	Product Name	Application	Type
PSBL-082	Human Anti-BSG Recombinant Antibody (clone 4A5); scFv Fragment	WB, ELISA, FuncS	Human scFv
FAMAB-0033CQ-S(P)	Mouse Anti-BSG Recombinant Antibody scFv Fragment (FAMAB-0033CQ-S(P))	ELISA, Block	Mouse scFv
HPAB-0126CQ-S(P)	Mouse Anti-BSG Recombinant Antibody (clone HAb18); scFv Fragment	ELISA, IF	Mouse scFv
PSBC-403	Mouse Anti-BSG Recombinant Antibody (clone 6H8); scFv Fragment	ELISA, FC	Mouse scFv
HPAB-3188LY-S(P)	Human Anti-BSG Recombinant Antibody (clone hPPAT-082-01); scfv Fragment	ELISA, FC	Humanized scfv

CAT	Product Name	Application	Type
TAB-1285CL-F(E)	Anti-Human BSG Recombinant Antibody Fab Fragment (2.6.1 (ABX-RB2))	Inhib	Fully human antibody
TAB-1287CL-F(E)	Human Anti-BSG Recombinant Antibody; Fab Fragment (TAB-1287CL-F(E))	FC	Human Fab
TAB-1288CL-F(E)	Human Anti-BSG Recombinant Antibody; Fab Fragment (TAB-1288CL-F(E))	FC	Human Fab
TAB-1289CL-F(E)	Human Anti-BSG Recombinant Antibody; Fab Fragment (TAB-1289CL-F(E))	FC	Human Fab
TAB-1290CL-F(E)	Human Anti-BSG Recombinant Antibody; Fab Fragment (TAB-1290CL-F(E))	FC	Human Fab

CAT	Product Name	Application	Type
NEUT-070CQ	Human Anti-BSG Recombinant Antibody (clone Ab-1)	ELISA, Block	Human IgG1, κ
NEUT-071CQ	Mouse Anti-BSG Recombinant Antibody (clone HIM6)	FC, WB, IHC, Block	Mouse IgG1, κ

CAT	Product Name	Application	Type
MOR-0389	Hi-Affi™ Rabbit Anti-BSG Recombinant Antibody (clone DS389AB)	ICC, IHC-P, WB	Rabbit IgG

CAT	Product Name	Application	Type
NS-020CN	Mouse Anti-BSG Recombinant Antibody (clone 5F6)	ELISA, Block, FuncS	Mouse IgG1
NS-020CN-F(E)	Mouse Anti-BSG Recombinant Antibody (clone 5F6); Fab Fragment	ELISA	Mouse Fab

CAT	Product Name	Application	Type
FAMAB-0033CQ-F(E)	Mouse Anti-BSG Recombinant Antibody Fab Fragment (FAMAB-0033CQ-F(E))	ELISA, Block	Mouse Fab
FAMAB-0034CQ-F(E)	Human Anti-BSG Recombinant Antibody Fab Fragment (FAMAB-0034CQ-F(E))	ELISA, Block	Chimeric (mouse/human) Fab
HPAB-0126CQ-F(E)	Mouse Anti-BSG Recombinant Antibody (clone HAb18); Fab Fragment	ELISA, IF	Mouse Fab
HPAB-M0438-YC-F(E)	Human Anti-BSG Recombinant Antibody; Fab Fragment (HPAB-M0438-YC-F(E))	ELISA, IHC, Inhib	Humanized Fab
HPAB-M0439-YC-F(E)	Human Anti-BSG Recombinant Antibody; Fab Fragment (HPAB-M0439-YC-F(E))	ELISA	Humanized Fab

CAT	Product Name	Application	Type
HPAB-M0438-YC	Human Anti-BSG Recombinant Antibody (HPAB-M0438-YC)	ELISA, IHC, Inhib	Humanized IgG
HPAB-M0439-YC	Human Anti-BSG Recombinant Antibody (HPAB-M0439-YC)	ELISA	Humanized IgG
FN-066CQ	Mouse Anti-BSG Recombinant Antibody (clone UM-8D6)	FC, FuncS, IP, WB	Mouse IgG1
HPAB-3079LY	Mouse Anti-BSG Recombinant Antibody (HPAB-3079LY)	IHC, Inhib	Mouse IgG
HPAB-3080LY	Human Anti-BSG Recombinant Antibody (HPAB-3080LY)	IHC, Inhib	Chimeric (mouse/human) IgG

CAT	Product Name	Application	Type
AFC-TAB-883	Afuco™ Anti-BSG ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-883)	IF, IP, Neut, FuncS, ELISA	ADCC enhanced antibody

CAT	Product Name	Application	Type
VS-0724-YC1484	AbPlus™ Anti-BSG Magnetic Beads (VS-0724-YC1484)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0125-FY33	Human Anti-BSG (clone HAb18) scFv-Fc Chimera	ELISA, IF, WB	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0425-YC238	Recombinant Anti-BSG Vesicular Antibody, EV Displayed (VS-0425-YC238)	ELISA, FC, Neut, Cell-uptake

CAT	Product Name	Application	Type
VS-0525-XY837	Anti-Mouse BSG Immunohistochemistry Kit	IHC
VS-0525-XY838	Anti-Rat BSG Immunohistochemistry Kit	IHC

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