Recombinant Anti-human BSG Intrabody [(D-Arg)9]
CAT#: IAB-B050(A)
Recombinant anti-BSG intrabody linked to (D-Arg)9 works within cells and specifically reacts with a human leukocyte surface molecule BSG, expressed in CHO cells. The intrabody has the ability to down-regulate EMMPRIN cell surface expression on colorectal cancer cell.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/74870/1466_A2_3_selected.jpg
Normal Tissue
Figure 2 Testis
Sertoli cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_4_6.jpg
Normal Tissue
Figure 3 Heart muscle
Cardiomyocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_B_6_6.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_7_3.jpg
Normal Tissue
Figure 6 Kidney
Collecting ducts Staining: Medium Intensity: Strong Quantity: <25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_7_5.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172270-BSG
❮
❯
Specifications
- Immunogen
- human basigin (Ok blood group)
- Host Species
- human
- Type
- scFv-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- human
- Applications
- Antibody assay: Western blot; Immunocytochemistry; Neutralization; Functional studies
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- BSG; basigin (Ok blood group); M6; OK; 5F7; TCSF; CD147; EMMPRIN; basigin; CD147 antigen; OK blood group antigen; collagenase stimulatory factor; leukocyte activation antigen M6; extracellular matrix metalloproteinase inducer; tumor cell-derived collagena
- Gene ID
- 682
- UniProt ID
- P35613
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B050(G) | Recombinant Anti-human BSG Intrabody [+36 GFP] | IF, FC, FuncS | scFv-(+36GFP) |
| IAB-B050(T) | Recombinant Anti-human BSG Intrabody [Tat] | WB, ICC, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-156 | Anti-Human CD147 Recombinant Antibody (TAB-156) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-082 | Human Anti-BSG Recombinant Antibody (clone 4A5) | WB, ELISA, FuncS | Human IgG |
| VS3-XY139 | Mouse Anti-BSG Recombinant Antibody, FITC (clone 4AHIM6) | FC, IF, IHC, WB | Mouse IgG1 |
| VS3-XY140 | Mouse Anti-BSG Recombinant Antibody, PE (clone 4AHIM6) | FC, IF, IHC, WB | Mouse IgG1 |
| VS3-FY168 | Recombinant Rabbit Anti-Bsg Antibody (clone R03-7C3) | WB, ICC, IF, IP | Rabbit IgG |
| VS3-FY169 | Recombinant Rabbit Anti-BSG Antibody (clone R04-5B3) | WB, IHC-F, IHC-P, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-082 | Human Anti-BSG Recombinant Antibody (clone 4A5); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| PSBC-403 | Mouse Anti-BSG Recombinant Antibody (clone 6H8); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-M0438-YC-S(P) | Human Anti-BSG Recombinant Antibody; scFv Fragment (HPAB-M0438-YC-S(P)) | ELISA, IHC, Inhib | Human scFv |
| HPAB-M0439-YC-S(P) | Human Anti-BSG Recombinant Antibody; scFv Fragment (HPAB-M0439-YC-S(P)) | ELISA | Human scFv |
| HPAB-M0440-YC-S(P) | Human Anti-BSG Recombinant Antibody; scFv Fragment (HPAB-M0440-YC-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-082 | Human Anti-BSG Recombinant Antibody (clone 4A5); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| HPAB-0126CQ-F(E) | Mouse Anti-BSG Recombinant Antibody (clone HAb18); Fab Fragment | ELISA, IF | Mouse Fab |
| PFBC-403 | Mouse Anti-BSG Recombinant Antibody (clone 6H8); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-3079LY-F(E) | Mouse Anti-BSG Recombinant Antibody; Fab Fragment (HPAB-3079LY-F(E)) | IHC, Inhib | Mouse Fab |
| HPAB-3080LY-F(E) | Human Anti-BSG Recombinant Antibody; Fab Fragment (HPAB-3080LY-F(E)) | IHC, Inhib | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1285CL | Anti-Human BSG Recombinant Antibody (2.6.1 (ABX-RB2)) | Inhib | Fully human antibody |
| TAB-1287CL | Human Anti-BSG Recombinant Antibody (TAB-1287CL) | Cyt, FC | Human IgG |
| TAB-1288CL | Human Anti-BSG Recombinant Antibody (TAB-1288CL) | Cyt, FC | Human IgG |
| TAB-1289CL | Human Anti-BSG Recombinant Antibody (TAB-1289CL) | Cyt, FC | Human IgG |
| TAB-1290CL | Human Anti-BSG Recombinant Antibody (TAB-1290CL) | Cyt, FC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-070CQ | Human Anti-BSG Recombinant Antibody (clone Ab-1) | ELISA, Block | Human IgG1, κ |
| NEUT-071CQ | Mouse Anti-BSG Recombinant Antibody (clone HIM6) | FC, WB, IHC, Block | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0389 | Hi-Affi™ Rabbit Anti-BSG Recombinant Antibody (clone DS389AB) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-020CN | Mouse Anti-BSG Recombinant Antibody (clone 5F6) | ELISA, Block, FuncS | Mouse IgG1 |
| NS-020CN-F(E) | Mouse Anti-BSG Recombinant Antibody (clone 5F6); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-156 | Afuco™ Anti-BSG ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-156) | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| AFC-TAB-883 | Afuco™ Anti-BSG ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-883) | IF, IP, Neut, FuncS, ELISA | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1484 | AbPlus™ Anti-BSG Magnetic Beads (VS-0724-YC1484) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY33 | Human Anti-BSG (clone HAb18) scFv-Fc Chimera | ELISA, IF, WB | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC238 | Recombinant Anti-BSG Vesicular Antibody, EV Displayed (VS-0425-YC238) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY837 | Anti-Mouse BSG Immunohistochemistry Kit | IHC | |
| VS-0525-XY838 | Anti-Rat BSG Immunohistochemistry Kit | IHC |
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