Recombinant Anti-F3 Vesicular Antibody, EV Displayed (VS-0425-YC631) (CAT#: VS-0425-YC631)
The Recombinant Anti-F3 Vesicular Antibody, EV Displayed (VS-0425-YC631) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to F3-expressed cells or tissues. F3 is a coagulation factor III, initiating blood coagulation cascades. It uniquely acts without requiring functional precursor circulation.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49292/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49292/if_selected.jpg

Figure 2 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69132/1343_C8_1_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69132/1343_C8_1_selected.jpg

Figure 3 IHC staining of human nasopharynx
(Immunohistochemical staining of human nasopharynx shows strong cytoplasmic positivity in respiratory epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/ihc_selected.jpg
(Immunohistochemical staining of human nasopharynx shows strong cytoplasmic positivity in respiratory epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/ihc_selected.jpg

Figure 4 Cerebral cortex
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_B_7_5.jpg
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_B_7_5.jpg

Figure 5 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_6_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_6_6.jpg

Figure 6 Placenta
(Decidual cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_2_7.jpg
(Decidual cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_2_7.jpg

Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- F3
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Coagulation factor III, tissue factor
- Biological Process
- Blood coagulation, Hemostasis
- Cellular Localization
- Vesicles
- Introduction
- This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
- Alternative Names
- CD142, TF
- Gene ID
- 2152
- UniProt ID
- P13726
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "F3"
Select a product category from the dropdown menu below to view related products.
Please select product type
Fab Antibodies
ScFv Antibodies
Humanized Antibodies
Mouse Antibodies
Deglycosylated Antibodies
Rabbit Monoclonal Antibodies
Human Antibodies
Epitope-Specific Antibodies
ADCC Enhanced Antibodies
IgG Antibodies
Antibody Magnetic Beads
NHP Antibodies
ScFv-Fc Chimeras
IHC Kits & Antibodies
CAT | Product Name | Application | Type |
---|---|---|---|
PFBZ-043 | Mouse Anti-F3 Recombinant Antibody (clone 5G9); Fab Fragment | Block | Mouse Fab |
PFBW-043 | Human Anti-F3 Recombinant Antibody (clone D3H44); Fab Fragment | WB, IHC, IF, FuncS | Humanized Fab |
HPAB-0113-YC-F(E) | Human Anti-F3 Recombinant Antibody; Fab Fragment (HPAB-0113-YC-F(E)) | ELISA, FC, Neut | Human Fab |
HPAB-0114-YC-F(E) | Mouse Anti-F3 Recombinant Antibody; Fab Fragment (HPAB-0114-YC-F(E)) | ELISA | Mouse Fab |
HPAB-0117-YC-F(E) | Mouse Anti-F3 Recombinant Antibody (clone H36.D2.B7); Fab Fragment | ELISA, WB | Mouse Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0425-YC631. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, SPR, Inhib, FuncS
Application: ELISA, Inhib, FC
Application: WB, ELISA, IF
Application: WB, ELISA, IF, FuncS, Apop, BA
Application: ELISA, FuncS, Neut, IF, WB, EM, Inhib, IHC
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.