Human Anti-F3 Recombinant Antibody (clone D3H44) (CAT#: PABW-043)
Recombinant Humanized Antibody (D3H44) is capable of binding to F3, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-F3 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-F3 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody recgonises a binding epitope located in the C-terminal part of the extracellular domain of TF.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49292/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49292/if_selected.jpg
Figure 2 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69132/1343_C8_1_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69132/1343_C8_1_selected.jpg
Figure 3 IHC staining of human nasopharynx
(Immunohistochemical staining of human nasopharynx shows strong cytoplasmic positivity in respiratory epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/ihc_selected.jpg
(Immunohistochemical staining of human nasopharynx shows strong cytoplasmic positivity in respiratory epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/ihc_selected.jpg
Figure 4 Cerebral cortex
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_B_7_5.jpg
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_B_7_5.jpg
Figure 5 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_6_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_6_6.jpg
Figure 6 Placenta
(Decidual cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_2_7.jpg
(Decidual cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_2_7.jpg
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
Specifications
- Immunogen
- Human coagulation factor III (thromboplastin, tissue factor)
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human F3
- Species Reactivity
- Human
- Clone
- D3H44
- Applications
- WB, IHC, IF, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- F3; coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; tissue factor
- Gene ID
- 2152
- UniProt ID
- P13726
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone D3H44"
See other products for "F3"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Humanized Antibody Products
Fab Antibody Products
ScFv Antibody Products
Mouse Antibody Products
Deglycosylated Antibody Products
Rabbit Monoclonal Antibody Products
Human Antibody Products
Epitope-Specific Antibody Products
ADCC Enhanced Antibody Products
Antibody Magnetic Beads
Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1092z | Mouse Anti-F3 Recombinant Antibody (clone 18C8) | WB, FC, ICC, FuncS | Mouse IgG1 |
| PABZ-043 | Mouse Anti-F3 Recombinant Antibody (clone 5G9) | Block | Mouse IgG |
| PABL-471 | Human Anti-F3 Recombinant Antibody (clone 10H10) | WB, IF, FuncS | Human IgG |
| HPAB-0172CQ | Human Anti-F3 Recombinant Antibody (HPAB-0172CQ) | ELISA, FC, ADCC | Chimeric (mouse/human) IgG1 |
| ZG-0661J | Rabbit Anti-F3 Recombinant Antibody (clone 8B10) | ELISA, WB, IHC | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for PABW-043. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: WB, ELISA, FuncS
-1.png)
Application: ELISA, FC, Block, SPR
Application: WB, IF, FuncS
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
