Mouse Anti-F3 (clone H36.D2.B7) scFv-Fc Chimera
CAT#: VS-0425-FY92
This fusion protein targets F3 (Thrombomodulin), a key regulatory protein involved in the anticoagulant pathway. By binding to F3, the scFv-Fc construct can modulate the blood coagulation process, with potential applications in treating thrombotic disorders and enhancing anticoagulant therapy.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49292/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69132/1343_C8_1_selected.jpg
Subcellular Location
Figure 3 IHC staining of human nasopharynx
Immunohistochemical staining of human nasopharynx shows strong cytoplasmic positivity in respiratory epithelial cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_B_7_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_6_6.jpg
Normal Tissue
Figure 6 Placenta
Decidual cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_2_7.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, U-2197)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
❮
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Specifications
- Immunogen
- Recombinant human tissue factor (rhTF)
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Human F3
- Species Reactivity
- Human
- Clone
- H36.D2.B7
- Applications
- ELISA, Inhibition
- Related Disease
- Disseminated Intravascular Coagulation and Carotid Artery Thrombosis
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- Coagulation Factor III, Tissue Factor; Coagulation Factor III (Thromboplastin, Tissue Factor); Tissue Factor; TF; Coagulation Factor III; Thromboplastin; CD142 Antigen; CD142; TFA
- Gene ID
- 2152
- UniProt ID
- P13726
- Long Name
- Coagulation Factor III, Tissue Factor
- Sequence Similarities
- Belongs to the tissue factor family.
- Cellular Localization
- Membrane, Secreted
- Protein Refseq
- NP_001171567.1; NP_001984.1
- Function
- Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone H36.D2.B7"
- CAT
- Product Name
See other products for "F3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-258CL | Human Anti-F3 Recombinant Antibody (TAB-258CL) | ELISA | Human IgG |
| TAB-276CQ-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-276CQ-S(P)) | ELISA, FC | Humanized scFv |
| TAB-278CQ-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-278CQ-S(P)) | ELISA, FC | Humanized scFv |
| PABX-180 | Recombinant Human Anti-TF Antibody (D3H44) | WB, ELISA, FuncS | IgG |
| PABX-180-F (E) | Recombinant Human Anti-TF Antibody Fab Fragment (D3H44) | WB, ELISA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-043 | Mouse Anti-F3 Recombinant Antibody (clone 5G9); Fab Fragment | Block | Mouse Fab |
| PFBW-043 | Human Anti-F3 Recombinant Antibody (clone D3H44); Fab Fragment | WB, IHC, IF, FuncS | Humanized Fab |
| HPAB-0113-YC-F(E) | Human Anti-F3 Recombinant Antibody; Fab Fragment (HPAB-0113-YC-F(E)) | ELISA, FC, Neut | Human Fab |
| HPAB-0114-YC-F(E) | Mouse Anti-F3 Recombinant Antibody; Fab Fragment (HPAB-0114-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-0117-YC-F(E) | Mouse Anti-F3 Recombinant Antibody (clone H36.D2.B7); Fab Fragment | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-468 | Human Anti-F3 Recombinant Antibody (clone 10H10); scFv Fragment | WB, IF, FuncS | Human scFv |
| HPAB-J0088-YC-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (HPAB-J0088-YC-S(P)) | ELISA, FC, IHC, FuncS | Human scFv |
| HPAB-J0089-YC-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (HPAB-J0089-YC-S(P)) | ELISA, FC, IHC, FuncS | Human scFv |
| HPAB-J0090-YC-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (HPAB-J0090-YC-S(P)) | ELISA, FC | Human scFv |
| HPAB-J0091-YC-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (HPAB-J0091-YC-S(P)) | ELISA, FC, IHC, Inhib, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-277CQ-S(P) | Mouse Anti-F3 Recombinant Antibody; scFv Fragment (TAB-277CQ-S(P)) | ELISA, FC | Mouse scFv |
| PABX-179 | Recombinant Mouse Anti-TF Antibody (D3) | WB, ELISA, IF, FuncS | IgG |
| PABX-177-S (P) | Recombinant Human Anti-TF Antibody scFv Fragment (D3h44) | WB, ELISA, Neut, FuncS | scFv |
| PABX-179-S (P) | Recombinant Mouse Anti-TF Antibody scFv Fragment (D3) | WB, ELISA, IF, FuncS | scFv |
| PABX-179-F (E) | Recombinant Mouse Anti-TF Antibody Fab Fragment (D3) | WB, ELISA, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-178LC | Recombinant Anti-Human F3 Antibody (Non-glycosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0373MZ | Recombinant Mouse Anti-Human Tissue Factor Antibody (clone BIUG-5265) | RIA, WB, ELISA | Mouse antibody |
| HPAB-0114-YC | Mouse Anti-F3 Recombinant Antibody (HPAB-0114-YC) | ELISA | Mouse IgG |
| HPAB-0117-YC | Mouse Anti-F3 Recombinant Antibody (clone H36.D2.B7) | ELISA, WB | Mouse IgG |
| VS3-FY530 | Recombinant Rabbit Anti-F3 Antibody (clone R04-7G2) | WB, IHC-P | Rabbit IgG |
| VS3-FY2093 | Rabbit Anti-F3 Recombinant Antibody (clone R01-8E5) | WB, IHC-Fr, IHC-P, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1226 | Hi-Affi™ Rabbit Anti-F3 Recombinant Antibody (clone DS1226AB) | WB, IHC-P, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-473CQ | Anti-Human F3 Recombinant Antibody (TAB-473CQ) | ELISA, IHC, FC, IP, IF, Inhib | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0573CQ | Mouse Anti-F3 Recombinant Antibody (clone hATR-5) | ELISA, Inhib | Mouse IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-473CQ | Afuco™ Anti-F3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-473CQ) | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1301 | AbPlus™ Anti-F3 Magnetic Beads (VS-0724-YC1301) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY78 | Mouse Anti-NHP F3 Recombinant Antibody (clone TF9-10H10) | ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC631 | Recombinant Anti-F3 Vesicular Antibody, EV Displayed (VS-0425-YC631) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2412 | Anti-F3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2413 | Anti-Mouse F3 Immunohistochemistry Kit | IHC |
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