Mouse Anti-F3 (clone H36.D2.B7) scFv-Fc Chimera (CAT#: VS-0425-FY92)

This fusion protein targets F3 (Thrombomodulin), a key regulatory protein involved in the anticoagulant pathway. By binding to F3, the scFv-Fc construct can modulate the blood coagulation process, with potential applications in treating thrombotic disorders and enhancing anticoagulant therapy.

Specific Inquiry
  • Size:

  • Conjugation:

  • Endotoxin:

  • Purity:

  • Formats:

  • Isotype Switching:

  • Fc Engineering:

  • Modalities:

Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

Sequences:
Isotype :
Purity :
Endotoxin :
Quantity :
Conjugation :
Fc Engineering :
Modalities :
Other Requirements:
We require custom production
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • Recombinant human tissue factor (rhTF)
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1, scFv-Fc
  • Specificity
  • Human F3
  • Species Reactivity
  • Human
  • Clone
  • H36.D2.B7
  • Applications
  • ELISA, Inhibition
  • Related Disease
  • Disseminated Intravascular Coagulation and Carotid Artery Thrombosis

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • The optimal dilution concentration is determined by the experiment.

Target

  • Alternative Names
  • Coagulation Factor III, Tissue Factor; Coagulation Factor III (Thromboplastin, Tissue Factor); Tissue Factor; TF; Coagulation Factor III; Thromboplastin; CD142 Antigen; CD142; TFA
  • Long Name
  • Coagulation Factor III, Tissue Factor
  • Sequence Similarities
  • Belongs to the tissue factor family.
  • Cellular Localization
  • Membrane, Secreted
  • Function
  • Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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