Afuco™ Anti-F3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-473CQ)

Name: Afuco™ Anti-F3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-473CQ)
SKU: AFC-TAB-473CQ
Rating: 5 (1 reviews)

CAT#: AFC-TAB-473CQ

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to F3. It is a human monoclonal antibody that can be potentially used in the treatment of Solid tumors.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49292/if_selected.jpg

Subcellular Location Figure 2 IF staining of human cell line HaCaT

Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69132/1343_C8_1_selected.jpg

Subcellular Location Figure 3 IHC staining of human nasopharynx

Immunohistochemical staining of human nasopharynx shows strong cytoplasmic positivity in respiratory epithelial cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/ihc_selected.jpg

Normal Tissue Figure 4 Cerebral cortex

Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_B_7_5.jpg

Normal Tissue Figure 5 Testis

Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_6_6.jpg

Normal Tissue Figure 6 Placenta

Decidual cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_2_7.jpg

RNA Expression Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, U-2197)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3

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Specifications

Immunogen
The details of the immunogen for this antibody are not available.

Host Species
Human

Derivation
Human

Type
ADCC enhanced antibody

Specificity
Human F3

Species Reactivity
Human

Applications
ELISA, IHC, FC, IP, IF, Inhib

Conjugate
Unconjugated

Generic Name
Tisotumab

Related Disease
Solid tumors

Product Property

Purity
>95% by SDS-PAGE

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
F3; coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; tissue factor;

Gene ID
2152

UniProt ID
P13726

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - AFC-TAB-473CQ.pdf

MSDS

MSDS - AFC-TAB-473CQ.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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