Recombinant Rabbit Anti-FLT1 Capture Antibody (clone R83-8I-2)

CAT#: VS3-WK1946

This antibody is a rabbit recombinant antibody against human FLT1. It was developed by immunization of rabbit with recombinant human FLT1 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. The sandwich ELISA was established using matched antibody pair R83-8I-2 and R74-3T-9. The clone R83-8I-2 can be used as a capture antibody in ELISA analysis to identify human FLT1.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 IF staining of human cell line BJ Figure 3 Testis Figure 4 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, HMC-1, HUVEC TERT2, WM-115)

Specifications

  • Immunogen
  • Recombinant human FLT1 protein
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human FLT1
  • Species Reactivity
  • Human
  • Clone
  • R83-8I-2
  • Conjugate
  • Unconjugated

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein A affinity purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 0.01M PBS, pH 7.2
  • Storage
  • Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • Fms Related Tyrosine Kinase 1; Vascular Permeability Factor Receptor; Fms-Related Tyrosine Kinase 1 (Vascular Endothelial Growth Factor/Vascular Permeability Factor Receptor); Vascular Endothelial Growth Factor Receptor 1; Tyrosine-Protein Kinase Receptor FLT; Tyrosine-Protein Kinase FRT; Fms-Like Tyrosine Kinase 1; EC 2.7.10.1
  • Long Name
  • Fms Related Tyrosine Kinase 1
  • Sequence Similarities
  • Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
  • Cellular Localization
  • Cell membrane, Cytoplasm, Endosome, Membrane, Secreted
  • Post Translation Modifications
  • N-glycosylated.
    Ubiquitinated after VEGFA-mediated autophosphorylation, leading to proteolytic degradation.
  • Function
  • Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a positive regulator of postnatal retinal hyaloid vessel regression (By similarity).
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

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Detection antibody

Isotype Control

Secondary Antibody

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