Recombinant Anti-TNFRSF17 Vesicular Antibody, EV Displayed (VS-0425-YC680) (CAT#: VS-0425-YC680)

• Application
• ELISA, FC, SPR, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• TNFRSF17

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• TNF receptor superfamily member 17

• Biological Process
• Adaptive immunity, Immunity

• Molecular Function
• Receptor

• Cellular Localization
• Golgi apparatus, Mitotic spindle

• Introduction
• The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

• Alternative Names
• BCM, BCMA, CD269, TNFRSF13A

• Gene ID
• 608

• UniProt ID
• Q02223

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