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    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    Human Anti-TNFRSF17 scFv-Fc Chimera (VS-0325-FY2)

    CAT#: VS-0325-FY2

    The anti-BCMA scFv-Fc antibody binds to human BCMA with an affinity of approximately 6.44 nM. When tested against NCI-H929 cells, it exhibits an EC₅₀ value of 17.68 nM. This antibody is utilized in various therapeutic and diagnostic applications targeting multiple myeloma and other BCMA-expressing malignancies. Its high specificity and affinity make it a valuable tool in research and potential therapeutic development for related diseases.

    Gene Expression
    ❮
    Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, RPMI-8226, U-266/70, U-266/84)
    ❯

    Specifications

    • Host Species
    • Human
    • Type
    • Human IgG1, scFv-Fc
    • Specificity
    • Human TNFRSF17
    • Species Reactivity
    • Human
    • Applications
    • Flow Cytometry
    • Related Disease
    • Cancer

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Target

    • Alternative Names
    • TNF Receptor Superfamily Member 17; B-Cell Maturation Protein; BCMA; BCM; Tumor Necrosis Factor Receptor Superfamily, Member 17; Tumor Necrosis Factor Receptor Superfamily Member 17
    • Long Name
    • TNF Receptor Superfamily Member 17
    • Cellular Localization
    • Cell membrane; Endomembrane system
    • Post Translation Modifications
    • Glycosylation at Asn42
      Modification sites at PhosphoSitePlus
      Glycosylation from GlyConnect TNR17_HUMAN (2978)
      Glycosylation from GlyGen 1 site
    • Function
    • Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
      Promotes B-cell survival and plays a role in the regulation of humoral immunity.
      Activates NF-kappa-B and JNK.
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    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Datasheet

    Datasheet - VS-0325-FY2.pdf

    MSDS

    MSDS - VS-0325-FY2.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

    Lot Number:

    Isotype Control

    • CAT
    • Product Name

    Secondary Antibody

    • CAT
    • Product Name

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