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CASP3

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The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]

Species Reactivity:
Human
Type:
Llama VHH
Application:
WB, ELISA, IHC, FuncS
Species Reactivity:
human
Type:
vhh-(D-Arg)9
Application:
WB, ICC, FuncS
Species Reactivity:
human
Type:
vhh-(+36GFP)
Application:
ICC, Neut, FuncS
Species Reactivity:
human
Type:
vhh-Tat
Application:
ELISA, WB, ICC, FuncS
Species Reactivity:
Human
Type:
Rabbit IgG
Application:
WB, IF, IHC
Species Reactivity:
Human
Type:
Rabbit IgG
Application:
WB, IHC, IP
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, Neut, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
RIA, ELISA, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
ELISA, IP, FuncS
Derivation:
Phage display library screening
Species Reactivity:
Human
Type:
IgG
Application:
ICC/IF, IHC-Fr, IHC-P, WB
Species Reactivity:
Human, Rat
Type:
Rabbit IgG
Application:
WB, IF, IHC, IP, FC
Species Reactivity:
Human, Mouse
Type:
IgG
Application:
WB, IF, ICC, IHC-P, FC
Species Reactivity:
Human, Mouse
Type:
Rabbit IgG
Application:
WB, IF, IHC, FC
Species Reactivity:
Human, Mouse
Type:
Rabbit IgG
Application:
WB, IF, IHC, FC
Species Reactivity:
Human
Type:
Mouse antibody
Application:
IHC-P, WB
Species Reactivity:
Human, Mouse
Type:
Rabbit IgG
Application:
WB, IF, IHC, IP, FC
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