Products
Loading...

CASP3

More+
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, Neut, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
RIA, ELISA, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
ELISA, IP, FuncS
Species Reactivity:
Human, Mouse
Type:
IgG
Application:
WB, IF, ICC, IHC-P, FC
Species Reactivity:
Human
Type:
Llama VHH
Application:
WB, ELISA, IHC, FuncS
Species Reactivity:
human
Type:
vhh-(D-Arg)9
Application:
WB, ICC, FuncS
Species Reactivity:
human
Type:
vhh-(+36GFP)
Application:
ICC, Neut, FuncS
Species Reactivity:
human
Type:
vhh-Tat
Application:
ELISA, WB, ICC, FuncS
Derivation:
Phage display library screening
Species Reactivity:
Human
Type:
IgG
Application:
ICC/IF, IHC-Fr, IHC-P, WB
Species Reactivity:
Human
Type:
Mouse antibody
Application:
IHC-P, WB
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-381-2994    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2018 Creative-Biolabs All Rights Reserved