Creative Biolabs is dedicated to speeding up research and discovery of target CD3 by providing high-quality, cutting-edge recombinant antibodies.
CD3 is a key component of the T-cell receptor complex and is involved in T-cell activation and immune response. In cancer immunotherapy, targeting CD3 can help stimulate the immune system to recognize and attack cancer cells. In autoimmune diseases, modulating CD3 activity can potentially regulate the overactive immune response. This approach aims to restore immune balance and reduce tissue damage. Furthermore, the target CD3 provides valuable insights for the development of novel therapeutic strategies and the improvement of existing treatments.
We offer high-quality and top-notch antibody products to meet the research demands of a wide range of research personnel regarding the target CD3 and its functions.
Cat. No. | Product Name | Target Species | Host Species | Applications |
HPAB-1909LY | Human Anti-CD3 Recombinant Antibody (HPAB-1909LY) | Human | Human | ELISA; FC |
HPAB-0543-WJ | Mouse Anti-CD3 Recombinant Antibody (clone YTH 12.5) | Human | Rat | ELISA; FC |
HPAB-0546-WJ | Human Anti-CD3 Recombinant Antibody (clone HuM291) | Human | Human | Inhib, FC |
HPAB-0441-YJ | Mouse Anti-CD3 Recombinant Antibody (clone m3E3) | Human | Mouse | ELISA; FC |
HPAB-1181WJ | Human Anti-CD3 Recombinant Antibody (clone CBLC-007) | Human | Human | ELISA |
To meet the demands of our customers, during the production process of antibody products, we have established a series of strict quality management systems to ensure the high quality of the products.
Fig.1 SDS-PAGE analysis of anti-CD3 antibody
(Cat# HPAB-M0467-YC-S(P), Creative Biolabs).
Fig.2 SEC-HPLC analysis of anti-CD3 antibody
(Cat# HPAB-M0467-YC-S(P), Creative Biolabs).
Fig.3 WB analysis of anti-CD3 antibody
(Cat# HPAB-M0467-YC-S(P), Creative Biolabs).
Fig.4 FC analysis of Jurkat cells incubated with anti-CD3 antibody
(Cat# HPAB-M0467-YC-S(P)).
We offer one-stop services ranging from gene synthesis to the production of high-quality recombinant antibodies. Based on this, we are capable of providing customers with superior antibody production services.
Fig.5 Milligram-scale recombinant antibody production.
Fig.6 Gram-scale recombinant antibody production
Creative Biolabs is dedicated to offering researchers the most comprehensive and state-of-the-art high-quality recombinant antibodies in various formats. The antibody formats encompass, including full length, Fab, scFv, scFv-Fc, sc-Fab, and so on.
Fig.7 Full Length Anti-CD3 Recombinant Antibody Production and Modalities
Cluster of differentiation 3
Table 1. Therapeutic approaches targeting CD3 in clinical development.
Research phase | Company | Classification | Indications | Details |
Launched - 2018 | Amgen KK |
Bispecific Antibody Cancer Immunotherapy |
Precursor B-cell lymphocytic leukemia | Bl**m*b is a CD3-directed bispecific antibody used in the treatment of Precursor B-cell lymphocytic leukemia. |
Launched - 2023 | Pfizer |
Bispecific Antibody Cancer Immunotherapy Human Monoclonal Antibody |
Multiple myeloma | E**ta*b is a CD3-directed human monoclonal antibody used in the treatment of Multiple myeloma. |
Launched - 2023 | Genmab |
Bispecific Antibody Cancer Immunotherapy |
Lymphoma | E**t*mab is a bispecific antibody that targets CD3 and is applicable for the treatment of Lymphoma. |
Registered - 2023 | Roche | Monoclonal Antibody | Diffuse large B-cell Lymphoma | G**ta*ab is a monoclonal antibody that targets CD3 and is applicable for the treatment of Diffuse large B-cell Lymphoma. |
Launched - 1993 | Janssen |
Cancer Immunotherapy Murine Monoclonal Antibody |
Transplant rejection | M**onab-CD3 is an antibody aimed at CD3 and can be used to alleviate organ rejection reactions. |
Launched - 2022 | Immunocore | TCR-Like Antibody | Melanoma | T**taf*sp is an antibody aimed at CD3 and can be utilized for the treatment of Melanoma. |
Launched - 2022 | Janssen |
Bispecific Antibody Cancer Immunotherapy Humanized Monoclonal Antibody |
Multiple myeloma | T**tamab is a humanized monoclonal antibody targeting CD3 and is capable of being used for the treatment of Multiple myeloma. |
Launched - 2023 | Sanofi | Humanized Monoclonal Antibody | Diabetes type 1 | T**z*mab is a humanized monoclonal antibody targeting CD3 and is capable of being used for the treatment of Diabetes type 1. |
Registered - 2023 | Janssen |
Bispecific Antibody Cancer Immunotherapy Humanized Monoclonal Antibody |
Multiple myeloma | T**et*mab is a humanized monoclonal antibody that targets CD3 and is applicable for the treatment of Multiple myeloma. |
Registered - 2024 | Amgen |
Bispecific Antibody Cancer Immunotherapy |
Cancer | T**ta*ab is a CD3-directed bispecific antibody used in the treatment of cancer. |
Pre-Registered | Regeneron |
Bispecific Antibody Cancer Immunotherapy |
Multiple myeloma | L**el**mab is a bispecific antibody aimed at CD3 and can be used in the treatment of multiple myeloma. |
Pre-Registered | Regeneron |
Bispecific Antibody Cancer Immunotherapy Human Monoclonal Antibody |
Diffuse large B-cell Lymphoma | O**ext*mab is an antibody aimed at CD3 and can be utilized for the treatment of Diffuse large B-cell Lymphoma. |
Phase III | Bristol-Myers Squibb |
Bispecific Antibody Cancer Immunotherapy Humanized Monoclonal Antibody |
Multiple myeloma | A**uc**mab is a humanized monoclonal antibody targeting CD3 and is capable of being used for the treatment of Multiple myeloma. |
Phase III | Immunocore |
Bispecific Antibody Cancer Immunotherapy |
Melanoma | B**ta*sp is a bispecific antibody targeting CD3 and is capable of being used for the treatment of Melanoma. |
Phase III | Tolerx | Humanized Monoclonal Antibody | Diabetes type 1 | O**iz*mab is an antibody aimed at CD3 and is available for the treatment of Diabetes type 1. |
Phase III | AbbVie |
Bispecific Antibody Cancer Immunotherapy |
Multiple myeloma | T*B-383* is a CD3-directed human monoclonal antibody used in the treatment of Multiple myeloma. |
Phase I/II | Boehringer Ingelheim |
Bispecific Antibody Cancer Immunotherapy |
Carcinoma | B*-764532 is an antibody aimed at CD3 and is available for the treatment of Carcinoma. |
Phase II | Light Chain Bioscience |
Cancer Immunotherapy Human Monoclonal Antibody |
Crohn's disease | F**lu*ab is a CD3-directed human monoclonal antibody used in the treatment of Crohn's disease. |
Phase II | Biocon | Chimeric Monoclonal Antibody | Transplant rejection | q-*3 is a chimeric monoclonal antibody aimed at CD3 and can be used to alleviate organ rejection reactions. |
Phase II | Tolera Therapeutics | Murine Monoclonal Antibody | Transplant rejection | T**-101 is a murine monoclonal antibody antibody that targets CD3 and is applicable for the treatment of Transplant rejection. |
Phase II | PDL BioPharma | Humanized Monoclonal Antibody | Crohn's disease | V***iz*mab is a humanized monoclonal antibody that targets CD3 and is applicable for the treatment of Crohn's disease. |
For more information on anti-CD3 recombinant antibody products, please do not hesitate to contact us. We hope to establish a beneficial collaboration with you.
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For Research Use Only. Not For Clinical Use.