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Insulin

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Anti-insulin Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This insulin is obtained from pigs and is similar to human insulin. It replaces the insulin that your body would normally make. It is a short-acting insulin. It works by helping blood sugar (glucose) get into cells so your body can use it for energy.
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Related Signaling Pathways
Insulin Signaling Pathway Insulin Signaling Pathway
Related Diseases
Type I Diabetes Mellitus Type I Diabetes Mellitus
Maturity Onset Diabetes of the Young Maturity Onset Diabetes of the Young
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