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Insulin

Anti-insulin Products

PE-A*02:01/Human INS (ALWGPDPAAA) MHC Tetramer (MHC-LC1682)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: PE
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APC-A*02:01/Human INS (AQWGPDPAAA) MHC Tetramer (MHC-LC906)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: APC
Compare

APC-DRB1*04:01/Human INS (GSLQPLALEGSLQKRG) MHC Tetramer (MHC-LC963)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: APC
Compare

APC-H2-K1/Human INS (LYLVCGERG) MHC Tetramer (MHC-LC978)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: APC
Compare

APC-H2-K1/Human INS (LYLVCGERV) MHC Tetramer (MHC-LC981)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: APC
Compare

APC-H2-K1/Human INS (LYLVCGERGF) MHC Tetramer (MHC-LC984)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: APC
Compare

APC-DQB1*03:02/Human INS (LVEALYLVCGERGG) MHC Tetramer (MHC-LC1149)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: LVEALYLVCGERGG
- Conjugate: APC
Compare

APC-A*02:01/Human INS (ALWGPDPAAA) MHC Tetramer (MHC-LC1683)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: APC
Compare

BV421-A*02:01/Human INS (AQWGPDPAAA) MHC Tetramer (MHC-LC907)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: BV421
Compare

BV421-DRB1*04:01/Human INS (GSLQPLALEGSLQKRG) MHC Tetramer (MHC-LC964)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: BV421
Compare

BV421-H2-K1/Human INS (LYLVCGERG) MHC Tetramer (MHC-LC979)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: BV421
Compare

BV421-H2-K1/Human INS (LYLVCGERV) MHC Tetramer (MHC-LC982)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: BV421
Compare

BV421-H2-K1/Human INS (LYLVCGERGF) MHC Tetramer (MHC-LC985)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: BV421
Compare

BV421-DQB1*03:02/Human INS (LVEALYLVCGERGG) MHC Tetramer (MHC-LC1150)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: LVEALYLVCGERGG
- Conjugate: BV421
Compare

BV421-A*02:01/Human INS (ALWGPDPAAA) MHC Tetramer (MHC-LC1684)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: BV421
Compare

PE-DQB1*03:01/Human INS (FVNQHLCGSHLVEAL) MHC Tetramer (MHC-LC3234)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
Compare

PE-DQB1*02:01/Human INS (FVNQHLCGSHLVEAL) MHC Tetramer (MHC-LC3235)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
Compare

PE-DRB1*01:01/Human INS (FVNQHLCGSHLVEAL) MHC Tetramer (MHC-LC3236)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
Compare

PE-DRB1*04:01/Human INS (FVNQHLCGSHLVEAL) MHC Tetramer (MHC-LC3237)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
Compare

PE-DRB1*07:01/Human INS (FVNQHLCGSHLVEAL) MHC Tetramer (MHC-LC3238)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
Compare

Recombinant Human Anti-INS Soluble TCR (clone FS17) (scTCR-157CQ-S(P))
- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
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Recombinant Human Anti-INS Soluble TCR (clone FS18) (scTCR-158CQ-S(P))
- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
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Recombinant Mouse Anti-INS Soluble TCR (clone G9C8) (scTCR-159CQ-S(P))
- Species Reactivity: Human
- Epitope: LYLVCGERG
- MHC: H-2Kd
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Recombinant Human Anti-INS Soluble TCR (clone 1C8) (scTCR-357CQ-S(P))
- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
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Recombinant Human Anti-INS Soluble TCR (clone 1E6) (scTCR-358CQ-S(P))
- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
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Recombinant Human Anti-INS Soluble TCR (clone 3F2) (scTCR-359CQ-S(P))
- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
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Mouse Anti-INS Recombinant Antibody (clone 123) (FAMAB-0182YC)
- Species Reactivity: Bovine
- Type: Mouse IgG1
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 124) (FAMAB-0183YC)
- Species Reactivity: Bovine
- Type: Mouse IgG2a
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 133) (FAMAB-0184YC)
- Species Reactivity: Bovine
- Type: Mouse IgG2a
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 125) (FAMAB-0185YC)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 127) (FAMAB-0186YC)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 193020) (FAMAB-0187YC)
- Species Reactivity: Mouse
- Type: Mouse IgG2b, κ
- Application: ELISA, WB
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Mouse Anti-INS Recombinant Antibody (clone 5E1) (MRO-0841-CN)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, IHC
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Rabbit Anti-INS Recombinant Antibody (clone CBACN-307) (MRO-0842-CN)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: IF, IHC
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Mouse Anti-INS Recombinant Antibody (clone A6-6) (MRO-0843-CN)
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: IHC, ELISA
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Rabbit Anti-INS Polyclonal Antibody (MRO-1977-CN) (MRO-1977-CN)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC, FC, ELISA
Compare

PE-DRB1*04:01/Human INS (GAGSLQPLALEGSLQKRG) MHC Tetramer (MHC-CN0909)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: PE
Compare

APC-DRB1*04:01/Human INS (GAGSLQPLALEGSLQKRG) MHC Tetramer (MHC-CN0910)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: APC
Compare

FITC-DRB1*04:01/Human INS (GAGSLQPLALEGSLQKRG) MHC Tetramer (MHC-CN0911)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: FITC
Compare

DRB1*04:01/Human INS (GAGSLQPLALEGSLQKRG) MHC Tetramer (MHC-CN0912)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: Unconjugated
Compare

PE-A*02:01/Human INS (HLVEALYLV) MHC Tetramer (MHC-CN0913)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: PE
Compare

APC-A*02:01/Human INS (HLVEALYLV) MHC Tetramer (MHC-CN0914)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: APC
Compare

FITC-A*02:01/Human INS (HLVEALYLV) MHC Tetramer (MHC-CN0915)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: FITC
Compare

A*02:01/Human INS (HLVEALYLV) MHC Tetramer (MHC-CN0916)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: Unconjugated
Compare

Human Anti-INS Recombinant Soluble TCR (clone (1E6)-2) (scTCR-0546YC-S(P))
- Epitope: AQWGPDPAAA
- MHC: HLA-A02
Compare

Human Anti-INS Recombinant Soluble TCR (clone (1E6)-3) (scTCR-0547YC-S(P))
- Species Reactivity: Human
- Epitope: RQFGPDFPTI
- MHC: HLA-A*02:01
Compare

Human Anti-INS Recombinant Soluble TCR (clone (1E6)-4) (scTCR-0548YC-S(P))
- Epitope: RQFGPDWIVA
- MHC: HLA-A02
Compare

Human Anti-INS Recombinant Soluble TCR (clone (1E6)-5) (scTCR-0549YC-S(P))
- Species Reactivity: Human
- Epitope: RQWGPDPAAV
- MHC: HLA-A*02:01
Compare

Human Anti-INS Recombinant Soluble TCR (clone (1E6)-6) (scTCR-0550YC-S(P))
- Species Reactivity: Human
- Epitope: YLGGPDFPTI
- MHC: HLA-A*02:01
Compare

Human Anti-INS Recombinant Soluble TCR (clone (1E6)-7) (scTCR-0551YC-S(P))
- Species Reactivity: Human
- Epitope: YQFGPDFPIA
- MHC: HLA-A*02:01
Compare

Mouse Anti-INS Recombinant Soluble TCR (clone BDC12-4.1) (scTCR-0552YC-S(P))
- Epitope: VEALYLVCGEEG
- MHC: H2 class II
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Human Anti-INS Recombinant Soluble TCR (clone A15) (scTCR-0553YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
Compare

Human Anti-INS Recombinant Soluble TCR (clone A16) (scTCR-0554YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
Compare

Human Anti-INS Recombinant Soluble TCR (clone TA5) (scTCR-0555YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
Compare

Human Anti-INS Recombinant Soluble TCR (clone TA6) (scTCR-0556YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
Compare

Human Anti-INS Recombinant Soluble TCR (clone TC6) (scTCR-0557YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone UB6) (scTCR-0558YC-S(P))
- Species Reactivity: Human
- Epitope: RLLPLLALL
- MHC: HLA-A*02:01
Compare

Human Anti-INS Recombinant Soluble TCR (clone VC4) (scTCR-0559YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
Compare

Human Anti-INS Recombinant Soluble TCR (clone VD4) (scTCR-0560YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone WB4) (scTCR-0561YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone WG10) (scTCR-0562YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Antibody (clone mAb48) (HPAB-1993-FY)
- Species Reactivity: Human
- Type: Human IgG3, κ
- Application: ELISA
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Recombinant Mouse Anti-Insulin/Proinsulin Antibody (clone E7C5) (MOB-0152MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, IHC-Fr
Compare

PE-A*02:01/Human INS (AQWGPDPAAA) MHC Tetramer (MHC-LC905)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: PE
Compare

PE-DRB1*04:01/Human INS (GSLQPLALEGSLQKRG) MHC Tetramer (MHC-LC962)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: PE
Compare

PE-H2-K1/Human INS (LYLVCGERG) MHC Tetramer (MHC-LC977)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: PE
Compare

PE-H2-K1/Human INS (LYLVCGERV) MHC Tetramer (MHC-LC980)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: PE
Compare

PE-H2-K1/Human INS (LYLVCGERGF) MHC Tetramer (MHC-LC983)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: PE
Compare

PE-DQB1*03:02/Human INS (LVEALYLVCGERGG) MHC Tetramer (MHC-LC1148)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: LVEALYLVCGERGG
- Conjugate: PE
Compare

Human Anti-INS Recombinant Antibody (clone mAb49) (HPAB-1994-FY)
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
Compare

DRB1*04:01/Human Proinsulin (GAGSLQPLALEGSLQKRG) MHC Monomer (MHC-YF029)
- Class: Class II
- Antigen: Proinsulin
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: Biotin
Compare

DRB1*04:01/Human Proinsulin (GIVEQCCTSICSLYQ) MHC Monomer (MHC-YF032)
- Class: Class II
- Antigen: Proinsulin
- Antigen Species: Human
- Peptide: GIVEQCCTSICSLYQ
- Conjugate: Biotin
Compare

A*02:01/Human Ins B. 10 (HLVEALYLV) MHC Monomer (MHC-YF236)
- Class: Class I
- Antigen: Ins B. 10
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: Biotin
Compare

Mouse Anti-INS Recombinant Antibody (clone CG7C7) (FAMAB-0352JF)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FuncS
Compare

Human Anti-INS Recombinant Antibody (clone mAb13) (HPAB-1995-FY)
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone AE9D6) (FAMAB-0353JF)
- Species Reactivity: Bovine
- Type: Mouse IgG1
- Application: ELISA, FuncS
Compare

Human Anti-INS Recombinant Antibody (clone mAb13); Fab Fragment (HPAB-1995-FY-F(E))
- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
Compare

Human Anti-INS Recombinant Antibody (clone mAb13); scFv Fragment (HPAB-1995-FY-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone CG7C7); Fab Fragment (FAMAB-0352JF-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FuncS
Compare

Mouse Anti-INS Recombinant Antibody (clone CG7C7); scFv Fragment (FAMAB-0352JF-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FuncS
Compare

Human Anti-INS Recombinant Antibody (clone mAb49); Fab Fragment (HPAB-1994-FY-F(E))
- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
Compare

Human Anti-INS Recombinant Antibody (clone mAb49); scFv Fragment (HPAB-1994-FY-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
Compare

Recombinant Anti-human INS VHH Single Domain Antibody (NAB-1554-VHH)
- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ICC, ChiP, FA, ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone YC182); Fab Fragment (DrMAB-1026)
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
Compare

Human Anti-INS Recombinant Antibody (clone mAb48); Fab Fragment (HPAB-1993-FY-F(E))
- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
Compare

Human Anti-INS Recombinant Antibody (clone mAb48); scFv Fragment (HPAB-1993-FY-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 123); scFv Fragment (FAMAB-0182-YC-S(P))
- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 124); scFv Fragment (FAMAB-0183-YC-S(P))
- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 133); scFv Fragment (FAMAB-0184-YC-S(P))
- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 125); scFv Fragment (FAMAB-0185-YC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 127); scFv Fragment (FAMAB-0186-YC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 193020); scFv Fragment (FAMAB-0187-YC-S(P))
- Species Reactivity: Mouse
- Type: Mouse scFv
- Application: ELISA, WB
Compare

Mouse Anti-INS Recombinant Antibody (clone 123); Fab Fragment (FAMAB-0182-YC-F(E))
- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 124); Fab Fragment (FAMAB-0183-YC-F(E))
- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 133); Fab Fragment (FAMAB-0184-YC-F(E))
- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 125); Fab Fragment (FAMAB-0185-YC-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 127); Fab Fragment (FAMAB-0186-YC-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 193020); Fab Fragment (FAMAB-0187-YC-F(E))
- Species Reactivity: Mouse
- Type: Mouse Fab
- Application: ELISA, WB
Compare

Rabbit Anti-INS Recombinant Antibody (clone DS1841AB) (MOR-1841)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P, WB
Compare

Rabbit Anti-INS Recombinant Antibody (clone TH140DS) (MOR-4627)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IF, ICC, IHC
Compare

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For Research Use Only. Not For Clinical Use.

This insulin is obtained from pigs and is similar to human insulin. It replaces the insulin that your body would normally make. It is a short-acting insulin. It works by helping blood sugar (glucose) get into cells so your body can use it for energy.

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Related Signaling Pathways

Insulin Signaling Pathway

Related Diseases

Type I Diabetes Mellitus

Maturity Onset Diabetes of the Young