Anti-Human CD276 Recombinant Antibody (TAB-117CL) (CAT#: TAB-117CL)

Recombinant Humanized monoclonal antibody expressed in CHO binding to Human CD276. This antibody is a first-in-class, humanized IgG1κ monoclonal antibody that recognizes human B7-H3, a novel member of the B7 family of immune regulators. This antibody has been Fc-engineered to further augment its tumor killing activity.

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SDS-PAGE

Figure 1 CD276 Recombinant Antibody (TAB-117CL) in SDS-PAGE

Figure 1 CD276 Recombinant Antibody (TAB-117CL) in SDS-PAGE

SDS-PAGE analysis of TAB-117CL in non-reduced (Lane 1) and β-mercaptoethanol-reduced (Lane 2) conditions.

SEC-HPLC

Figure 2 CD276 Recombinant Antibody (TAB-117CL) in HPLC

Figure 2 CD276 Recombinant Antibody (TAB-117CL) in HPLC

The purity of TAB-117CL was greater than 95% as determined by SEC-HPLC.


Specifications

  • Derivation
  • Humanized
  • Type
  • Antibody
  • Species Reactivity
  • Human
  • Applications
  • ADCC, FuncS
  • Related Disease
  • Solid Tumors

Product Property

  • Purity
  • 90–95% (SDS-PAGE)
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

Applications

  • Application Notes
  • This antibody has been tested for use in Antibody-dependent Cellular Cytotoxicity Assay and Functional Assay.

Target

  • Alternative Names
  • CD276; CD276 molecule; B7H3; B7-H3; B7RP-2; 4Ig-B7-H

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-117CL, RRID: AB_3111822)

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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