Human B7-H3 can be special recognized by a recombinant mouse IgG1, κ antibody (HPAB-0238-CN). The antibody can cross react with cynomolgus and was produced by the hybridomas. The formation of such a complex can occur in vitro or in vivo. The monoclonal antibody can bind to B7-H3 through the extracellular domain of B7-H3 and may subsequently be internalized. The B7-H3 antibody demonstrates a cleaner normal tissue immunohistochemistry (IHC) profile, a stronger tumor/normal tissue IHC differential, moderate to strong binding ability (IHC), and cross-reactivity with monkey B7-H3. HPAB-0238-CN-F(E) antibody is the Fab fragment antibody form of HPAB-0238-CN antibody. Fab fragments, the antigen-binding domains of an antibody molecule, consist of two amino acid chains composed of VH+CH1 and VL+CL domains.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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