Human Anti-DKK1 Recombinant Antibody (HPAB-0278-YC) (CAT#: HPAB-0278-YC)
The product is a recombinant antibody that specifically bind DKK1 polypeptides. The binding region for the mAb includes two discontinuous portions, the first from amino acids 98 to 104 and a region from amino acids 107-121 and 127-140. The antibody can bind to DKK1 to protect all cleavage sites on D1 domain from trypsin proteolysis.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, CACO-2, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107984-DKK1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107984-DKK1
Specifications
- Immunogen
- Recombinant FLAG-tagged human DKK1 (FLAG-DKK1) and recombinant Fc-tagged human DKK1 (DKK1-fc)
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human DKK1
- Species Reactivity
- Human
- Applications
- ELISA, Block, FuncS
- Related Disease
- Cancer, Diabetes
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Dickkopf WNT Signaling Pathway Inhibitor 1; HDkk-1; DKK-1; SK; Dickkopf (Xenopus Laevis) Homolog 1; Dickkopf 1 Homolog (Xenopus Laevis); Dickkopf Related Protein-1; Dickkopf-Like Protein 1; Dickkopf 1 Homolog; Dickkopf-1 Like; Dickkopf-1
- Gene ID
- 22943
- UniProt ID
- O94907
Related Resources
Canonical Wnt Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-193MZ | Anti-Human DKK1 Recombinant Antibody (huMabJC18) | ELISA | Humanized antibody |
| TAB-193MZ-S(P) | Anti-Human DKK1 Recombinant Antibody scFv Fragment (huMabJC18) | ELISA | Humanized antibody |
| TAB-193MZ-F(E) | Anti-Human DKK1 Recombinant Antibody Fab Fragment (huMabJC18) | ELISA | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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