Anti-Human FGF2 Recombinant Antibody (3F12E7) (CAT#: TAB-048WM)
Recombinant monoclonal antibody to FGF-2. Clone 3F12E7 is a mouse monoclonal antibody which can be potentially used for the prophylaxis and treatment of metastatic melanoma tumors.
Specific Inquiry
WB
Figure 1 Immunoblotting analysis of anti-FGF2 3F12E7 mAb reactivity with B16-F10 tumor protein extracts.
de Aguiar, R. B., Parise, C. B., Souza, C. R. T., Braggion, C., Quintilio, W., Moro, A. M., ... & de Moraes, J. Z. (2016). Blocking FGF2 with a new specific monoclonal antibody impairs angiogenesis and experimental metastatic melanoma, suggesting a potential role in adjuvant settings. Cancer letters, 371(2), 151-160.
ELISA
Figure 2 ELISA detection of the 3F12E7 mAb inhibition of biotinlabeled FGF2 (200 ng/mL) binding to FGFR1.
de Aguiar, R. B., Parise, C. B., Souza, C. R. T., Braggion, C., Quintilio, W., Moro, A. M., ... & de Moraes, J. Z. (2016). Blocking FGF2 with a new specific monoclonal antibody impairs angiogenesis and experimental metastatic melanoma, suggesting a potential role in adjuvant settings. Cancer letters, 371(2), 151-160.
IHC
Figure 3 Anti-FGF2 3F12E7 mAb reduces CD34+ vessel density in B16-F10 lung tumor foci.
de Aguiar, R. B., Parise, C. B., Souza, C. R. T., Braggion, C., Quintilio, W., Moro, A. M., ... & de Moraes, J. Z. (2016). Blocking FGF2 with a new specific monoclonal antibody impairs angiogenesis and experimental metastatic melanoma, suggesting a potential role in adjuvant settings. Cancer letters, 371(2), 151-160.
Specifications
- Immunogen
- Vector uP-hFGF2 containing a human FGF2 cDNA sequence
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human, Mouse
- Clone
- 3F12E7
- Applications
- ELISA, WB, IHC, FuncS
- Related Disease
- Metastatic melanoma tumors
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Western Blot, Immunohistochemistry, Function Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- FGF2; fibroblast growth factor 2 (basic); BFGF; FGFB; FGF-2; HBGF-2; fibroblast growth factor 2; prostatropin; heparin-binding growth factor 2; basic fibroblast growth factor bFGF
- Gene ID
- 2247
- UniProt ID
- P09038
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 3F12E7"
See other products for "FGF2"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-357-F(E) | Recombinant Anti-human FGF2 Antibody Fab Fragment | IF, FC, FuncS | Fab |
| MHH-357-F(E) | Recombinant Human Anti-human FGF2 Antibody Fab Fragment | IP, IF, Biosensors, FuncS | Fab |
| HPAB-0164-WJ-F(E) | Mouse Anti-FGF2 Recombinant Antibody (clone E12); Fab Fragment | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-357-S(P) | Recombinant Anti-human FGF2 Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| MHH-357-S(P) | Recombinant Human Anti-human FGF2 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| HPAB-0164-WJ-S(P) | Mouse Anti-FGF2 Recombinant Antibody (clone E12); scFv Fragment | ELISA | Mouse scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-357 | Recombinant Human Anti-human FGF2 Antibody | RIA, IF, FuncS | IgG |
| MOB-0725CT | Recombinant Mouse anti-Human FGF2 Monoclonal antibody (3D9) | ELISA | |
| MOB-094LC | Mouse Anti-FGF2 Recombinant Antibody (clone GAL-F2) | ELISA, FuncS, WB | Mouse IgG |
| MRO-0576-CN | Rabbit Anti-FGF2 Recombinant Antibody (clone JM28-10) | WB, IP, FC | Rabbit IgG |
| VS3-XY701 | Mouse Anti-FGF2 Recombinant Antibody (clone 2H5G2C11) | ELISA, WB, IHC |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-279CL | Human Anti-FGF2 Recombinant Antibody (TAB-279CL) | ELISA | Human IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-049WM | Anti-Human FGF2 Recombinant Antibody (6) | ELISA, WB | Human Antibody |
| TAB-049WM-S(P) | Anti-Human FGF2 Recombinant Antibody scFv Fragment (6) | ELISA, WB | Human Antibody |
| TAB-049WM-F(E) | Anti-Human FGF2 Recombinant Antibody Fab Fragment (6) | ELISA, WB | Human Antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-048WM-S(P) | Anti-Human FGF2 Recombinant Antibody scFv Fragment (3F12E7) | ELISA, FuncS | |
| TAB-048WM-F(E) | Anti-Human FGF2 Recombinant Antibody Fab Fragment (3F12E7) | ELISA, FuncS |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-800CQ | Mouse Anti-FGF2 Recombinant Antibody (clone 0.T.50) | Neut | Mouse IgG1, κ |
| NEUT-801CQ | Mouse Anti-FGF2 Recombinant Antibody (clone CBL979) | Neut | Mouse IgG1, κ |
| NEUT-802CQ | Recombinant Mouse Anti-FGF2 Antibody (FB-8) | RIA, ELISA, Dot, Neut, WB, IHC-FoFr | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1293 | Hi-Affi™ Rabbit Anti-FGF2 Recombinant Antibody (clone DS1293AB) | FC, IP, WB | Rabbit IgG |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-009CN | Human Anti-FGF2 Recombinant Antibody (clone YC055) | ELISA | Humanized IgG |
| NS-026CN | Mouse Anti-FGF2 Recombinant Antibody (clone Dan-2) | ELISA, FC | Mouse IgG |
| NS-009CN-F(E) | Human Anti-FGF2 Recombinant Antibody (clone YC056); Fab Fragment | ELISA | Humanized Fab |
| NS-026CN-F(E) | Mouse Anti-FGF2 Recombinant Antibody (clone YC058); Fab Fragment | ELISA, FC | Mouse Fab |
| NS-009CN-S(P) | Human Anti-FGF2 Recombinant Antibody (clone YC054); scFv Fragment | ELISA | Humanized scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-048WM. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.