Human Anti-FGFR4 Recombinant Antibody (clone BM1); Fab Fragment (CAT#: HPAB-0059-LS-F(E))
The antibody is used to bind the FGF receptor 4 (FGFR4) and the medical use thereof, in particular for the diagnosis prevention or treatment of diseases associated with FGFR expression, overexpression or hyperactivity.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human smooth muscle
(Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27273/ihc_selected.jpg
(Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27273/ihc_selected.jpg
Figure 2 IHC staining of human gall bladder
(Immunohistochemical staining of human gall bladder shows strong cytoplasmic and membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/ihc_selected.jpg
(Immunohistochemical staining of human gall bladder shows strong cytoplasmic and membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/ihc_selected.jpg
Figure 3 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5196/ihc_selected.jpg
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5196/ihc_selected.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_3.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_4.jpg
Figure 6 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_7_5.jpg
Figure 7 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_4_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_4_6.jpg
Figure 8 RNA cell line category: Group enriched (CACO-2, Hep G2, RH-30)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160867-FGFR4
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160867-FGFR4
Specifications
- Immunogen
- FGFR4
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human Fab
- Specificity
- Human FGFR4
- Species Reactivity
- Human
- Clone
- BM1
- Applications
- Inhib, ELISA, WB
- Related Disease
- Hepatocellular cancer, Breast cancer, Prostate cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-066WM | Anti-Human FGFR4 Recombinant Antibody (XPA.48.056) | ELISA, FC | Human Antibody |
| TAB-066WM-S(P) | Anti-Human FGFR4 Recombinant Antibody scFv Fragment (XPA.48.056) | ELISA, FC | Human Antibody |
| TAB-066WM-F(E) | Anti-Human FGFR4 Recombinant Antibody Fab Fragment (XPA.48.056) | ELISA, FC | Human Antibody |
| TAB-384CQ | Human Anti-FGFR4 Recombinant Antibody (TAB-384CQ) | ELISA | Human IgG |
| TAB-384CQ-S(P) | Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (TAB-384CQ-S(P)) | ELISA | Human scFv |
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