Human Anti-FGFR4 Recombinant Antibody (clone BM1) (CAT#: HPAB-0059-LS)
The antibody is used to bind the FGF receptor 4 (FGFR4) and the medical use thereof, in particular for the diagnosis prevention or treatment of diseases associated with FGFR expression, overexpression or hyperactivity.
Specific Inquiry
ADCC
Figure 1 Three examples of anti-FGFR4 antibodies are capable of mediating antibody-dependent cellular cytotoxicity in HepG2 cells (Panel A), HuH-7 cells (Panel B) and HCT116-FGFR4 cells (Panel C).
Percent specific cytotoxicity was calculated using 1 or 10 mg/ml antibody.
Specifications
- Immunogen
- FGFR4
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human IgG
- Specificity
- Human FGFR4
- Species Reactivity
- Human
- Clone
- BM1
- Applications
- Inhib, ELISA, WB
- Related Disease
- Hepatocellular cancer, Breast cancer, Prostate cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in ADCC.
Target
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3383z | Mouse Anti-FGFR4 Recombinant Antibody (clone 31F7) | WB, IP, IF, IHC, ELISA | Mouse IgG1, κ |
| HPAB-0054-LS | Human Anti-FGFR4 Recombinant Antibody (HPAB-0054-LS) | Inhib | Human IgG |
| HPAB-0055-LS | Human Anti-FGFR4 Recombinant Antibody (HPAB-0055-LS) | Inhib | Human IgG |
| ZG-0344J | Mouse Anti-FGFR4 Recombinant Antibody (ZG-0344J) | WB, IF, ELISA | Mouse IgG |
| ZG-0345J | Mouse Anti-FGFR4 Recombinant Antibody (ZG-0345J) | WB, IHC, ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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