Rabbit Anti-GRB2 Recombinant Antibody (clone DS1379AB)
CAT#: MOR-1379
Recombinant Rabbit anti-GAB2 monoclonal antibody for WB, ICC/IF, FC, IP, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & nucleoli.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30749/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30750/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows cytoplasmic and nuclear positivity in germinal and non germinal center .
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2589/7330_A_4_8_selected.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2589/7330_A_7_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2589/7330_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2589/7330_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2589/7330_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177885-GRB2
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Specifications
- Immunogen
- Synthetic peptide corresponding to residues in human Gab2.
- Host Species
- Rabbit
- Derivation
- Phage display library
- Type
- Rabbit IgG
- Specificity
- Human GRB2
- Species Reactivity
- Human
- Clone
- DS1379AB
- Applications
- WB, ICC, IF, FC, IP
- Conjugate
- Unconjugated
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Growth Factor Receptor Bound Protein 2; SH2/SH3 Adapter GRB2; Protein Ash; ASH; Epidermal Growth Factor Receptor-Binding Protein GRB2; Growth Factor Receptor-Bound Protein 2; Growth Factor Receptor-Bound Protein 3; Abundant SRC Homology; Adapter Protein GRB2; EGFRBP-GRB2; MSTP084; Grb3-3; MST084; NCKAP2; HT027
- Gene ID
- 2885
- UniProt ID
- P62993
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Related Diseases
Breast Cancer
Colorectal Cancer
Endometrial Cancer
Gastric Cancer
Non-small Cell Lung Cancer
Prostate Cancer
Throid Cancer
Insulin Resistance
Alcoholism
Related Signaling Pathways
ErbB Signaling Pathway
FcεR1 Signaling Pathway
MAPK Signaling Pathway
mTOR Signaling Pathway
PPAR Signaling Pathway
Ras Signaling Pathway
TCR Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "GRB2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2552z | Mouse Anti-GRB2 Recombinant Antibody (clone 39A1) | WB, ELISA | Mouse IgG1 |
| MOB-1410MZ | Recombinant Mouse Anti-Human GRB2 Antibody (clone S22) | WB | Mouse antibody |
| FAMAB-1154CQ | Mouse Anti-GRB2 Recombinant Antibody (clone SAIC-19D-1F4) | Immuno-MRM, WB | Mouse IgG1 |
| ZG-0693J | Rabbit Anti-GRB2 Recombinant Antibody (clone 6E1) | ELISA, WB, IHC | Rabbit IgG |
| VS4-WK202 | Mouse Anti-GRB2 Recombinant Antibody (VS4-WK202) | ELISA, WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0235MZ | Chicken Anti-GRB2 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1502 | Rabbit Anti-GRB2 Recombinant Antibody (clone DS1502AB) | WB, IP, IHC-P, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY949 | Anti-GRB2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2906 | Anti-Mouse GRB2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2905 | Anti-Human GRB2 Immunohistochemistry Kit | IHC |
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