Anti-GD2 Antibody-Cytokine Fusion Protein, IgG-IL12 (CAT#: ACFP-SH142)

• Target
• GD2

• Molecule Class
• IgG2-IL12

• Species Reactivity
• Human

• Expression Host
• CHO

• Clone
• 14.18

• Related Disease
• Neuroblastomas, Medulloblastomas, Astrocytomas, Melanomas, Small-cell lung cancer, Osteosarcomas and other soft tissue sarcomas.

• Cytokine 1
• IL12

• Cytokines 1 Description
• Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation. IL-12 is composed of a bundle of four alpha helices. It is a heterodimeric cytokine encoded by two separate genes, IL-12A (p35) and IL-12B (p40). The active heterodimer (referred to as 'p70'), and a homodimer of p40 are formed following protein synthesis.

• Cytokine 1 Species
• Human

• Applications
• This product can be used therapeutically to deliver biologically active ligands to a desired tissue.

• Alternative Names
• Disialoganglioside GD2; Ganglioside G2; GD2

• ACFP-SH002
• Anti-GD2 Antibody-Cytokine Fusion Protein, IgG-IL2

• ACFP-SH003
• Anti-GD2 Antibody-Cytokine Fusion Protein, scFv-Fc-IL2

• ACFP-SH176
• Anti-GD2 Antibody-Cytokine Fusion Protein, IgG-IL12-IL2

• ACFP-SH141
• Anti-GD2 Antibody-Cytokine Fusion Protein, IgG-ala-IL12

• ACFP-SH177
• Anti-GD2 Antibody-Cytokine Fusion Protein, IgG (14.18)-IL12-IL2

• ACFP-SH178
• Anti-GD2 Antibody-Cytokine Fusion Protein, IgG (14.18)-IL12-IL2

• ACFP-SH188
• Anti-GD2 Antibody-Cytokine Fusion Protein, IgG-IL12-GM-CSF

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