1 0
Cart
    Inquiry
    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    Afuco™ Anti-GD2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-731)

    CAT#: AFC-TAB-731

    This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant chimeric (human/Mouse) antibody expressed in CHO binding to human GD2. It is a chimeric monoclonal antibody that induces antibody dependent cell-mediated cytotoxicity. It is intended as maintenance therapy (targeting minimal residual disease) for high risk neuroblastoma, administered after induction therapy, autologous stem cell transplantation and/or radiotherapy.

    Specifications

    • Immunogen
    • The details of the immunogen for this antibody are not available.
    • Host Species
    • Chimeric
    • Derivation
    • Chimeric (mouse/human)
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Applications
    • Neut, ELISA, IF, IP, FuncS, FC
    • Conjugate
    • Unconjugated
    • Trade name
    • Unituxin
    • Generic Name
    • Dinutuximab
    • Related Disease
    • Neuroblastoma

    Product Property

    • Purity
    • >95% by SDS-PAGE
    • Storage
    • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • Disialoganglioside GD2; Ganglioside G2; GD2
    REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS
    Inquiry
    Navs

    Customer Review

    Submit a review or a question

    There are currently no Customer reviews or questions for AFC-TAB-731. Click the button above to contact us or submit your feedback about this product.

    Submit Your Publication

    Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

    Article title:
    DOI/PubMed URL:
    Email:
    Name:

    This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

    Biosimilar Overview

    Please refer to Dinutuximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Dinutuximab.

    Downloadable Resources

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Datasheet

    Datasheet - AFC-TAB-731.pdf

    MSDS

    MSDS - AFC-TAB-731.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

    Lot Number:

    Protocol & Troubleshooting

    Immunofluorescence (IF)

    We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

    See other products for "Dinutuximab"

    DrugMonitor™ Anti-Dinutuximab Antibody (VS-1224-YC361)
    Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody targeting GD2, used in immunotherapy strategies to treat neuroblastoma and prevent relapse. The DrugMonitor™ Anti-Dinutuximab Antibody (VS-1224-YC361) is an anti-drug antibody (ADA) against Dinutuximab. This drug-based antibody is raised in mice immunized with the Dinutuximab. The anti-Dinutuximab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Dinutuximab in samples.

    See other products for "GD2"

    Select a product category from the dropdown menu below to view related products.

    CAT Product Name Application Type
    NAB-770-sdAb Recombinant Anti-Human GD2 VHH Single Domain Antibody Neut, ChiP, IP, FUNC Llama VHH
    CAT Product Name Application Type
    TAB-731 Anti-GD2 Recombinant Antibody (TAB-731) Neut, ELISA, IF, IP, FuncS, FC, ICC IgG1 - kappa
    CAT Product Name Application Type
    AGTO-L018R anti-GD2 immunotoxin 14G2a (IgG)-RTA Cytotoxicity assay, Functional assay
    CAT Product Name Application Type
    TAB-304CL Anti-Human GD2 Recombinant Antibody (hu14.18K322A) FC, FuncS Antibody
    PABX-059 Human Anti-GD2 Recombinant Antibody (PABX-059) FuncS IgG1, κ
    PABX-059-F (E) Human Anti-GD2 Recombinant Antibody; Fab Fragment (PABX-059-F (E)) FC, ELISA, FuncS Human Fab
    CAT Product Name Application Type
    PABL-100 Mouse Anti-GD2 Recombinant Antibody (clone 14G2a) ELISA, WB, FuncS Mouse IgG
    PABL-101 Mouse Anti-GD2 Recombinant Antibody (clone 3F8) FC, ELISA, FuncS Mouse IgG
    HPAB-0701-CN Human Anti-GD2 Recombinant Antibody (clone AB527) ELISA, FC, IHC, IF Human IgM
    HPAB-1524WJ Human Anti-GD2 Recombinant Antibody (clone KM8138) ELISA, WB Human IgG
    HPAB-1525WJ Human Anti-GD2 Recombinant Antibody (clone KM1138) ELISA, WB Human IgG
    CAT Product Name Application Type
    PSBL-100 Mouse Anti-GD2 Recombinant Antibody (clone 14G2a); scFv Fragment ELISA, WB, FuncS Mouse scFv
    PSBL-101 Mouse Anti-GD2 Recombinant Antibody (clone 3F8); scFv Fragment FC, ELISA, FuncS Mouse scFv
    MOB-181CQ Human Anti-GD2 Recombinant Antibody (MOB-181CQ) ELISA, FC, FuncS Humanized scFv
    HPAB-0701-CN-S(P) Human Anti-GD2 Recombinant Antibody (clone AB527); scFv Fragment ELISA, FC, IHC, IF Human scFv
    HPAB-1030WJ-S(P) Mouse Anti-GD2 Recombinant Antibody; scFv Fragment (HPAB-1030WJ-S(P)) ELISA Mouse scFv
    CAT Product Name Application Type
    PFBZ-049 Mouse Anti-GD2 Recombinant Antibody (clone ME36.1); Fab Fragment WB, FuncS Mouse Fab
    HPAB-0701-CN-F(E) Human Anti-GD2 Recombinant Antibody (clone AB527); Fab Fragment ELISA, FC, IHC, IF Human Fab
    HPAB-0027-WJ-F(E) Mouse Anti-GD2 Recombinant Antibody; Fab Fragment (HPAB-0027-WJ-F(E)) ELISA, RIA Mouse Fab
    HPAB-1524WJ-F(E) Human Anti-GD2 Recombinant Antibody; Fab Fragment (clone KM8138) ELISA, WB Human Fab
    HPAB-1525WJ-F(E) Human Anti-GD2 Recombinant Antibody; Fab Fragment (clone KM1138) ELISA, WB Human Fab
    CAT Product Name Application Type
    TAB-075CQ Human Anti-GD2 Recombinant Antibody (TAB-075CQ) ELISA, FC Human IgM, κ
    CAT Product Name Application Type
    TAB-074CQ-S(P) Human Anti-GD2 Recombinant Antibody; scFv Fragment (TAB-074CQ-S(P)) ELISA, FC Human scFv
    TAB-075CQ-S(P) Human Anti-GD2 Recombinant Antibody; scFv Fragment (TAB-075CQ-S(P)) ELISA, FC Human scFv
    TAB-076CQ-S(P) Human Anti-GD2 Recombinant Antibody; scFv Fragment (TAB-076CQ-S(P)) ELISA, FC Human scFv
    TAB-077CQ-S(P) Human Anti-GD2 Recombinant Antibody; scFv Fragment (TAB-077CQ-S(P)) ELISA, FC Human scFv
    TAB-078CQ-S(P) Human Anti-GD2 Recombinant Antibody; scFv Fragment (TAB-078CQ-S(P)) ELISA, FC Human scFv
    CAT Product Name Application Type
    NS-029CN Mouse Anti-GD2 Recombinant Antibody (clone 5F11) WB Mouse IgG
    NS-030CN Mouse Anti-GD2 Recombinant Antibody (clone 3G6) WB Mouse IgG
    NS-029CN-F(E) Mouse Anti-GD2 Recombinant Antibody (clone 5F11); Fab Fragment WB Mouse Fab
    NS-030CN-F(E) Mouse Anti-GD2 Recombinant Antibody (clone 3G6); Fab Fragment WB Mouse Fab
    NS-029CN-S(P) Mouse Anti-GD2 Recombinant Antibody (clone 5F11); scFv Fragment WB Mouse scFv
    CAT Product Name Application Type
    VS-0125-FY63 Human Anti-GD2 (clone 3F8) scFv-Fc Chimera FC, ELISA, FuncS, ADCC, Cyt Human IgG1, scFv-Fc
    Specific Inquiry
    Go to compare Add to compare
    Request
    Custom Production     custom production
    See Our Custom Production in Action
    Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE
    Download the full case study
    Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE
    Download the full case study

    Popular Products

    Figure 5 Anti-Human ITGAV Recombinant Antibody (TAB-H01) in ELISA

    Anti-Human ITGAV Recombinant Antibody (Abituzumab) (CAT# TAB-H01)
    Application: Inhib, Agonist

    Figure 2 Anti-Human Met (TAB-190-F(E)) in ELISA

    Anti-Human Met(Onartuzumab) (CAT# TAB-190-F(E))
    Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

    Figure 11 Blockade of PD-1/PD-L1 interaction by anti-PD-1 antibody (Cat# TAB-H55) resulted in an increase of IFN-γ production.

    Human Anti-PDCD1 Recombinant Antibody (TAB-H55) (CAT# TAB-H55)
    Application: Inhib, Agonist

    Figure 9 Anti-IAV HA Recombinant Antibody (PABL-213) in DB

    Recombinant Human Anti-IAV HA Antibody (CT149) (CAT# PABL-213)
    Application: WB, Neut, FuncS

    Figure 2 Anti-Human EGFR Antibody (PABW-088) in DB

    Mouse Anti-EGFR Recombinant Antibody (clone 7A7) (CAT# PABW-088)
    Application: ELISA, WB

    Figure 3 Human Anti-MS4A1 Recombinant Antibody (PABL-422) in Flow Cytometry

    Human Anti-MS4A1 Recombinant Antibody (clone 2F2) (CAT# PABL-422)
    Application: WB, ELISA, FuncS

    Figure 3 Anti-Human EFNB2 Recombinant Antibody scFv Fragment (B11) (TAB-390MZ-S(P)) in Dot Blot

    Anti-Human EFNB2 Recombinant Antibody scFv Fragment (B11) (CAT# TAB-390MZ-S(P))
    Application: ELISA

    Figure 3 Anti-Human IgE Antibody (TAB-095ZJ) in ELISA

    Anti-Human IgE Single Domain Antibody (TAB-095ZJ), Research Grade Biosimilar (CAT# TAB-095ZJ)
    Application: ELISA, Inhib, FC

    Figure 2 Anti-Human TREM1 Recombinant Antibody (TAB-167CQ) in SDS-PAGE

    Human Anti-TREM1 Recombinant Antibody (TAB-167CQ) (CAT# TAB-167CQ)
    Application: ELISA, FC, WB, Block

    Figure 1 Anti-Human SLC1A5 Antibody (TAB-1010CLV) in FC

    Anti-Human SLC1A5 Recombinant Antibody (TAB-1010CLV) (CAT# TAB-1010CLV)
    Application: FC, ADCC, CDC

    Figure 3 Human Anti-Human ERBB3 Antibody (TAB-422CQ) in DB

    Anti-Human ERBB3 Recombinant Antibody (TAB-422CQ) (CAT# TAB-422CQ)
    Application: ELISA, IHC, FC, IP, IF, BL

    Figure 3 Recombinant Anti-IL17A Antibody (HPAB-0208-LSX) in ELISA

    Human Anti-IL17A Recombinant Antibody (HPAB-0208-LSX) (CAT# HPAB-0208-LSX)
    Application: ELISA, FuncS

    Figure 5 Rabbit Anti-T7 RNA Polymerase Antibody, HRP (MOB-0296MC-HRP) in Dot Blot

    Rabbit Anti-T7 RNA Polymerase Antibody (CAT# MOB-0296MC)
    Application: ELISA, WB

    Figure 5 Human Anti-FGFR2 Recombinant Antibody (NS-027CN) in Dot Blot

    Human Anti-FGFR2 Recombinant Antibody (clone M048-D01) (CAT# NS-027CN)
    Application: ELISA, WB, FC

    Figure 7 Anti-EBV gH/gL Antibody (PABC-419) in ELISA

    Recombinant Mouse Anti-EBV gH/gL Antibody (CL40) (CAT# PABC-419)
    Application: ELISA, Inhib, FC, Neut

    Figure 2 Recombinant Human Anti-WTA Antibody(HPAB-N0298-YC) in HPLC

    Human Anti-WTA Recombinant Antibody (HPAB-N0298-YC) (CAT# HPAB-N0298-YC)
    Application: FuncS

    Figure 2 Human Anti-FRβ Recombinant Antibody (m909) (HPAB-0792-FY) in ELISA.

    Human Anti-FRβ Recombinant Antibody (HPAB-0792-FY) (CAT# HPAB-0792-FY)
    Application: ELISA

    Figure 2 Human Anti-HLA-B27 Recombinant Antibody (clone HD5) (HPAB-J0121-YC) in SDS-PAGE

    Human Anti-HLA-B27 Recombinant Antibody (clone HD5) (CAT# HPAB-J0121-YC)
    Application: ELISA, Block, WB, FC, IP

    Figure 5 Mouse Anti-Fc P329G LALA Antibody (PABJ-0115) in DB

    Mouse Anti-Fc P329G LALA Recombinant Antibody (clone P329G LALA) (CAT# PABJ-0115)
    Application: ELISA, FuncS

    Figure 3 Mouse Anti-E-Tag Antibody (ZG-0287U) in ELISA

    Mouse Anti-E-Tag Recombinant Antibody (clone 11H12B3) (CAT# ZG-0287U)
    Application: ELISA, WB, IP

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

    Send Inquiry

    This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

    Go to compare

    Go to compare