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GD2

Anti-GD2 Products

Mouse Anti-GD2 Recombinant Antibody (clone 5F11) (NS-029CN)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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Mouse Anti-GD2 Recombinant Antibody (clone 14G2a); scFv Fragment (PSBL-100)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, FuncS
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Mouse Anti-GD2 Recombinant Antibody (clone 3F8) (PABL-101)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, ELISA, FuncS
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Anti-Human GD2 Recombinant Antibody (hu14.18K322A) (TAB-304CL)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
- Application: FC, FuncS
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Mouse Anti-GD2 Recombinant Antibody (clone 7A4) (FAMAB-0126YC)
- Species Reactivity: Human
- Type: Mouse IgG3, κ
- Application: ELISA
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Human Anti-GD2 Recombinant Antibody (PABX-059) (PABX-059)
- Derivation: Human
- Species Reactivity: Human
- Type: IgG1, κ
- Application: FuncS
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Human Anti-GD2 Recombinant Antibody; scFv Fragment (PABX-059-S (P)) (PABX-059-S (P))
- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: FC, ELISA, FuncS
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Human Anti-GD2 Recombinant Antibody; Fab Fragment (PABX-059-F (E)) (PABX-059-F (E))
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: FC, ELISA, FuncS
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Mouse Anti-GD2 Recombinant Antibody (clone ME36.1) (PABZ-049)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, FuncS
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Human Anti-GD2 Recombinant Antibody (TAB-074CQ) (TAB-074CQ)
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody (TAB-075CQ) (TAB-075CQ)
- Species Reactivity: Human
- Type: Human IgM, κ
- Application: ELISA, FC
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Mouse Anti-GD2 Recombinant Antibody (clone 14G2a) (PABL-100)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB, FuncS
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Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-078CQ-F(E)) (TAB-078CQ-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody (clone AB527) (HPAB-0701-CN)
- Species Reactivity: Human
- Type: Human IgM
- Application: ELISA, FC, IHC, IF
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Mouse Anti-GD2 Recombinant Antibody (HPAB-0027-WJ) (HPAB-0027-WJ)
- Species Reactivity: Human
- Type: Mouse IgG3, κ
- Application: ELISA, RIA
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Human Anti-GD2 Recombinant Antibody; scFv Fragment (TAB-077CQ-S(P)) (TAB-077CQ-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody; scFv Fragment (TAB-078CQ-S(P)) (TAB-078CQ-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-074CQ-F(E)) (TAB-074CQ-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-075CQ-F(E)) (TAB-075CQ-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-076CQ-F(E)) (TAB-076CQ-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-077CQ-F(E)) (TAB-077CQ-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody (TAB-076CQ) (TAB-076CQ)
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody (TAB-077CQ) (TAB-077CQ)
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody (TAB-078CQ) (TAB-078CQ)
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody; scFv Fragment (TAB-074CQ-S(P)) (TAB-074CQ-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody; scFv Fragment (TAB-075CQ-S(P)) (TAB-075CQ-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
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Human Anti-GD2 Recombinant Antibody; scFv Fragment (TAB-076CQ-S(P)) (TAB-076CQ-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
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Afuco™ Anti-Human GD2 ADCC Recombinant Antibody (hu14.18K322A), ADCC Enhanced (AFC-291CL)
- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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Anti-GD2 Recombinant Antibody (TAB-731) (TAB-731)
- Derivation: Chimeric (Human/Mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
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Mouse Anti-GD2 Antibody (clone ME36.1), mRNA (PABZ-049-mRNA)
- Species Reactivity: Human
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Human Anti-GD2 Recombinant Antibody (clone KM1138) (HPAB-1525WJ)
- Derivation: Chimeric
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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Human Anti-GD2 Recombinant Antibody (clone KM8138) (HPAB-1524WJ)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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Afuco™ Anti-GD2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-731) (AFC-TAB-731)
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: Neut, ELISA, IF, IP, FuncS, FC
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Human Anti-GD2 Recombinant Antibody (HPAB-1030WJ) (HPAB-1030WJ)
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA
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Mouse Anti-GD2 Recombinant Antibody; scFv Fragment (HPAB-1030WJ-S(P)) (HPAB-1030WJ-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Human Anti-GD2 Recombinant Antibody; Fab Fragment (HPAB-1030WJ-F(E)) (HPAB-1030WJ-F(E))
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA
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Mouse Anti-GD2 Recombinant Antibody (clone 7A4); scFv Fragment (FAMAB-0126-YC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Mouse Anti-GD2 Recombinant Antibody (clone 7A4); Fab Fragment (FAMAB-0126-YC-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Mouse Anti-GD2 Recombinant Antibody; scFv Fragment (HPAB-0027-WJ-S(P)) (HPAB-0027-WJ-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, RIA
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Mouse Anti-GD2 Recombinant Antibody; Fab Fragment (HPAB-0027-WJ-F(E)) (HPAB-0027-WJ-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, RIA
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Human Anti-GD2 Recombinant Antibody; Fab Fragment (clone KM8138) (HPAB-1524WJ-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
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Human Anti-GD2 Recombinant Antibody; Fab Fragment (clone KM1138) (HPAB-1525WJ-F(E))
- Derivation: Chimeric
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
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Human Anti-GD2 Recombinant Antibody; scFv Fragment (clone KM8138) (HPAB-1524WJ-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
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Human Anti-GD2 Recombinant Antibody; scFv Fragment (clone KM1138) (HPAB-1525WJ-S(P))
- Derivation: Chimeric
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
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anti-GD2 immunotoxin 14G2a (IgG)-RTA (AGTO-L018R)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG-IL2 (ACFP-SH002)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Mouse-Dog)
- Cytokine 1 Species: Dog
- Molecule Class: L kappa; IgG1-IL2
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Mouse Anti-GD2 Recombinant Antibody (clone 3F8); Fab Fragment (PFBL-101)
- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, ELISA, FuncS
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Mouse Anti-GD2 Recombinant Antibody (clone 3G6) (NS-030CN)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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Mouse Anti-GD2 Recombinant Antibody (clone 5F11); Fab Fragment (NS-029CN-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB
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Mouse Anti-GD2 Recombinant Antibody (clone 3G6); Fab Fragment (NS-030CN-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB
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Mouse Anti-GD2 Recombinant Antibody (clone 5F11); scFv Fragment (NS-029CN-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB
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Mouse Anti-GD2 Recombinant Antibody (clone 3G6); scFv Fragment (NS-030CN-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB
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Human Anti-GD2 Recombinant Antibody (clone AB527); scFv Fragment (HPAB-0701-CN-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC, IHC, IF
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Human Anti-GD2 Recombinant Antibody (clone AB527); Fab Fragment (HPAB-0701-CN-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, IHC, IF
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Recombinant Anti-Human GD2 VHH Single Domain Antibody (NAB-770-sdAb)
- Species Reactivity: Human
- Type: Llama VHH
- Application: Neut, ChiP, IP, FUNC
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG-IL12-GM-CSF (ACFP-SH188)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: IL12
- Cytokine 2: GM-CSF
- Host: Mouse
- Cytokine 1 Species: Human
- Cytokine 2 Species: Human
- Molecule Class: IgG3-IL12-GM-CSF
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Mouse Anti-GD2 Recombinant Antibody (clone ME36.1); Fab Fragment (PFBZ-049)
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, FuncS
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Mouse Anti-GD2 Recombinant Antibody (clone ME36.1); scFv Fragment (PSBZ-049)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, FuncS
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Human Anti-GD2 Recombinant Antibody (MOB-181CQ) (MOB-181CQ)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC, FuncS
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Mouse Anti-GD2 Recombinant Antibody (clone 3F8); scFv Fragment (PSBL-101)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA, FuncS
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Mouse Anti-GD2 Recombinant Antibody (clone 14G2a); Fab Fragment (PFBL-100)
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB, FuncS
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG-ala-IL12 (ACFP-SH141)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: IgG2-ala-IL12
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG-IL12 (ACFP-SH142)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: IgG2-IL12
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG (ch14.18)-RLI (ACFP-SH143)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: RLI
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG2-RLI
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG (ch14.18)-TNFα (ACFP-SH144)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: TNFα
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG1-TNFα
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG-IL12-IL2 (ACFP-SH176)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: IL12
- Cytokine 2: IL2
- Host: Mouse
- Cytokine 1 Species: Human
- Cytokine 2 Species: Human
- Molecule Class: IgG3-IL12-IL2
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG (14.18)-IL12-IL2 (ACFP-SH177)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: IL12
- Cytokine 2: IL2
- Host: Mouse
- Cytokine 1 Species: Mouse
- Cytokine 2 Species: Mouse
- Molecule Class: L kappa; IgG1-IL12-IL2
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Anti-GD2 Antibody-Cytokine Fusion Protein, scFv-Fc-IL2 (ACFP-SH003)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Mouse-Dog)
- Cytokine 1 Species: Dog
- Molecule Class: scFv-Fc-IL2
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG (ch14.18)-IL2 (ACFP-SH019)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG1-IL2
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG (ch14.18)-LT (ACFP-SH020)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: LT
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG1-LT
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG (ch14.18)-GM-CSF (ACFP-SH021)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: GM-CSF
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: IgG1-GM-CSF
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG (hu14.18)-IL2 (ACFP-SH030)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG1-IL2
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Anti-GD2 Antibody-Cytokine Fusion Protein, IgG (hu14.18)-IL2 (ACFP-SH046)
- Target: GD2
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG1-IL2
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Human Anti-GD2 (clone 3F8) scFv-Fc Chimera (VS-0125-FY63)
- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: FC, ELISA, FuncS, ADCC, Cyt
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For Research Use Only. Not For Clinical Use.

GD2 is a disialic ganglioside expressed in tumors of neuroectodermal origin (including human neuroblastoma and melanoma), and its expression in normal tissues (mainly human cerebellum and peripheral nerves) is highly restricted.
The relative tumor-specific expression of GD2 makes it a suitable target for immunotherapy using monoclonal antibodies or artificial T cell receptors. An example of such an antibody is hu14.18K322A, a monoclonal antibody. The anti-GD2 antibody is currently in phase II clinical trials for the treatment of previously untreated high-risk neuroblastoma and combined chemotherapy prior to stem cell transplantation and radiation therapy. A previous phase I clinical trial designed to reduce toxicity in patients with refractory or recurrent neuroblastoma found a safe dose and determined that common toxicity, especially pain, can be well controlled.