Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (A10F9) (CAT#: PABX-089-S (P))
Anti-HIV-1 antibody is a Mouse of scFv class that binds to an HIV-1.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 SDS-PAGE and western blotting of the assembled CA N21C/A22C-V5.
Lane M, molecular weight marker; lane 1, protein before assembly; lane 2-5, protein after assembly. The primary antibody is a CA specific mAb A10F11.
Zhang, Z., He, M., Bai, S., Zhang, F., Jiang, J., Zheng, Q., ... & Xia, N. (2018). T= 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display. Viruses, 10(12), 667.
Figure 2 Antigenicity of CA N21C/A22C-V3 was determined with the A10F11 mAb using indirect ELISA.
Data were analyzed by GraphPad Prism software. The 50% maximal effective concentration (EC52) was calculated by a four-parameter logistic fit, and is indicated in the square brackets.
Zhang, Z., He, M., Bai, S., Zhang, F., Jiang, J., Zheng, Q., ... & Xia, N. (2018). T= 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display. Viruses, 10(12), 667.
Figure 3 Ribbon representation of a detailed view of p24 CTD recognition by the A10F11 Fab fragment.
The residues involved in protein-protein interactions are indicated and shown in stick mode.
Gu, Y., Cao, F., Wang, L., Hou, W., Zhang, J., Hew, C. L., ... & Xia, N. (2013). Structure of a novel shoulder-to-shoulder p24 dimer in complex with the broad-spectrum antibody A10F9 and its implication in capsid assembly. PloS one, 8(4), e61316.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- scFv
- Specificity
- Tested positive against native D. pteronyssinus Derp1
- Species Reactivity
- Human immunodeficiency virus 1
- Clone
- A10F9
- Applications
- Neut (assay-depended)
FuncS (assay-depended)
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- Assay-depended
Target
- Alternative Names
- HIV-1; human immunodeficiency virus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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