Anti-IGF2 Recombinant Antibody (Dusigitumab)
CAT#: TAB-740
Recombinant human monoclonal antibody expressed in CHO binding to human IGF2. Dusigitumab is a human monoclonal antibody designed for the treatment of cancer.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7993/1030_B7_2_selected.jpg
Normal Tissue
Figure 2 High expression in placenta
Decidual cells Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7556/156845_A_2_7.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (CACO-2, Hep G2, LHCN-M2, RH-30, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167244-IGF2
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG2
- Species Reactivity
- Human
- Applications
- Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, IHC and most other immunological methods.
- CAS
- 1204390-13-5
- Generic Name
- dusigitumab
- MW
- 151 kDa
- Related Disease
- Breast cancers
Product Property
- Purity
- >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
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Related Diseases
Endocrine Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Dusigitumab"
Afuco™ Anti-IGF2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-740)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant human monoclonal antibody expressed in CHO binding to human IGF2. It is a human monoclonal antibody designed for the treatment of cancer.
DrugMonitor™ Anti-Dusigitumab Antibody (VS-1224-YC382)Dusigitumab is a human monoclonal antibody targeting IGF2, investigated in trials for cancer, advanced solid malignancies, unresectable or metastatic hepatocellular carcinoma (HCC), and hormone-sensitive, HER-2 negative metastatic breast cancer. The DrugMonitor™ Anti-Dusigitumab Antibody (VS-1224-YC382) is an anti-drug antibody (ADA) against Dusigitumab. This drug-based antibody is raised in mice immunized with the Dusigitumab. The anti-Dusigitumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Dusigitumab in samples.
See other products for "IGF2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-387CL | Anti-Human IGF2 Recombinant Antibody (DX-2647) | BL, Inhib | Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-231 | Human Anti-IGF2 Recombinant Antibody (PABL-231) | WB, ELISA, FuncS | Human IgG |
| MRO-0818-CN | Rabbit Anti-IGF2 Recombinant Antibody (clone CBACN-300) | WB, IF, IHC | Rabbit IgG |
| HPAB-0613-WJ | Human Anti-IGF2 Recombinant Antibody (clone m610.27) | ELISA, Inhib | Humanized IgG1 |
| MOB-251YJL | Rabbit Anti-IGF2 Recombinant Antibody (clone CBI236) | ELISA | Rabbit IgG |
| VS3-FY735 | Recombinant Mouse Anti-IGF2 Antibody (clone 4F1-6D6-2D10) | IHC-P | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-231 | Human Anti-IGF2 Recombinant Antibody scFv Fragment (PSBL-231) | WB, ELISA, FuncS | Human scFv |
| HPAB-0613-WJ-S(P) | Human Anti-IGF2 Recombinant Antibody (clone m610.27); scFv Fragment | ELISA, WB | Humanized scFv |
| HPAB-1733-FY-F(E) | Human Anti-IGF2 Recombinant Antibody (clone M606); scFv Fragment | Inhib, WB, ELISA | Human scFv |
| HPAB-1734-FY-F(E) | Human Anti-IGF2 Recombinant Antibody (clone m610); scFv Fragment | Inhib, WB, ELISA | Human scFv |
| HPAB-1735-FY-F(E) | Human Anti-IGF2 Recombinant Antibody (clone m616); scFv Fragment | Inhib, WB, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-231 | Human Anti-IGF2 Recombinant Antibody Fab Fragment (PFBL-231) | WB, ELISA, FuncS | Human Fab |
| HPAB-0037LY-F(E) | Human Anti-IGF2 Recombinant Antibody; Fab Fragment (HPAB-0037LY-F(E)) | WB | Human Fab |
| HPAB-0613-WJ-F(E) | Human Anti-IGF2 Recombinant Antibody (clone m610.27); Fab Fragment | ELISA, WB | Humanized Fab |
| HPAB-1733-FY-S(P) | Human Anti-IGF2 Recombinant Antibody (clone M606); Fab Fragment | Inhib, WB, ELISA | Human Fab |
| HPAB-1734-FY-S(P) | Human Anti-IGF2 Recombinant Antibody (clone m610); Fab Fragment | Inhib, WB, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1083CQ | Mouse Anti-IGF2 Recombinant Antibody (clone CBL493) | Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1756 | Rabbit Anti-IGF2 Recombinant Antibody (clone DS1756AB) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-740 | Afuco™ Anti-IGF2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-740) | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC84 | Recombinant Anti-IGF2 Vesicular Antibody, EV Displayed (VS-0425-YC84) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3433 | Anti-IGF2 Immunohistochemistry Kit | IHC |
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