Hi-Affi™ Recombinant Rabbit Anti-LRP6 Monoclonal Antibody (DS2087AB)

Name: Hi-Affi™ Recombinant Rabbit Anti-LRP6 Monoclonal Antibody (DS2087AB)
SKU: MOR-2087
Rating: 5 (1 reviews)

CAT#: MOR-2087

Recombinant Rabbit anti-LRP6 monoclonal antibody for ICC/IF, WB, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IHC staining of human colon

Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4490/ihc_selected.jpg

Normal Tissue Figure 2 IHC staining of human kidney

High expression. RNA expression: 4.4 nTPM

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29925/ihc_selected.jpg

Normal Tissue Figure 3 IHC staining of human lymph node

Low expression. RNA expression: 0.8 nTPM

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29925/62204_A_7_8_val_selected.jpg

Normal Tissue Figure 4 Cerebral cortex

Neuronal cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4490/12171_B_8_5.jpg

Normal Tissue Figure 5 Liver

Cholangiocytes
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4490/12026_A_8_4.jpg

Normal Tissue Figure 6 Testis

Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4490/12026_A_4_6.jpg

RNA Expression Figure 7 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000070018-LRP6

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Specifications

Immunogen
A phospho specific peptide corresponding to residues surrounding serine 1490 of human LRP6.

Host Species
Rabbit

Derivation
Phage display library screening

Type
IgG

Species Reactivity
Human

Clone
DS2087AB

Applications
Used for immunoassay techniques such as: Immunocytochemistry/Immunofluorescence; Western Blot

Conjugate
Unconjugated

Product Property

Purification
Purified with Absolute Mag™ Protein A Agarose

Purity
> 95% as determined by both RP-HPLC and SDS-PAGE analysis.

Format
Liquid

Storage
Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.

Target

Alternative Names
ADCAD2; STHAG7

Gene ID
4040

UniProt ID
O75581

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Related Signaling Pathways

Canonical Wnt Signaling Pathway

JAK-STAT Signaling Pathway

Non-Canonical Wnt Signaling Pathway

Related Diseases

Hepatocellular Carcinoma

Pancreatic Cancer

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MOR-2087.pdf

MSDS

MSDS - MOR-2087.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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