Recombinant Mouse Antibody (M2139) is capable of binding to Mouse J1 , expressed in Chinese Hamster Ovary cells (CHO). This mAb specifically recognizes the J1 epitope and is the most arthritogenic anti-CII mAb in the mouse, eliciting disease upon single transfer.
Figure 1 Western blot analysis antibody M2139 binding to recombinant IdeS.
Recombinant IdeS was incubated with purified monoclonal antibody (mAb) M287 (IgG2a), CIIC1 (IgG2a), M2139 (IgG2b), M284 (IgG1), or B10 (IgG3), separated by sodium dodecyl sulfate–polyacrylamide gel electrophoresis under reducing conditions on Precise Protein Gradient Gels, and stained with Coomassie blue.
Nandakumar, K. S., Johansson, B. P., Björck, L., & Holmdahl, R. (2007). Blocking of experimental arthritis by cleavage of IgG antibodies in vivo. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology, 56(10), 3253-3260.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-225-S(P) | Recombinant Anti-human COL2A1 Antibody scFv Fragment | WB, FC, FuncS | scFv |
MHH-225-S(P) | Recombinant Human Anti-human COL2A1 Antibody scFv Fragment | WB, IP, FuncS | scFv |
PSBZ-088 | Mouse Anti-COL2A1 Recombinant Antibody (clone ACC4); scFv Fragment | ELISA, IP, IHC | Mouse scFv |
HPAB-0281-YC-S(P) | Human Anti-COL2A1 Recombinant Antibody; scFv Fragment (HPAB-0281-YC-S(P)) | ELISA, IHC, FuncS | Human scFv |
PSBC-248 | Mouse Anti-COL2A1 Recombinant Antibody (clone ACC1); scFv Fragment | ELISA, IHC | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MHH-225-F(E) | Recombinant Human Anti-human COL2A1 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
PFBZ-088 | Mouse Anti-COL2A1 Recombinant Antibody (clone ACC4); Fab Fragment | ELISA, IP, IHC | Mouse Fab |
PFBL-644 | Mouse Anti-COL2A1 Recombinant Antibody (clone M2139); Fab Fragment | ELISA | Mouse Fab |
HPAB-0281-YC-F(E) | Human Anti-COL2A1 Recombinant Antibody; Fab Fragment (HPAB-0281-YC-F(E)) | ELISA, IHC, FuncS | Human Fab |
PFBC-248 | Mouse Anti-COL2A1 Recombinant Antibody (clone ACC1); Fab Fragment | ELISA, IHC | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABC-248 | Mouse Anti-COL2A1 Recombinant Antibody (clone ACC1) | ELISA, IHC | Mouse IgG |
MOR-0006-FY | Mouse Anti-COL2A1 Recombinant Antibody (clone M2139) | FuncS, IA | Mouse IgG2b |
VS3-QX258 | Mouse Anti-COL2A1 Recombinant Antibody (clone 5F4-4D3-9A6) | IHC | Mouse IgG1 |
VS3-QX259 | Mouse Anti-COL2A1 Recombinant Antibody (clone 9C3-9H6-2G7) | IHC | Mouse IgG1 |
VS3-QX260 | Mouse Anti-COL2A1 Recombinant Antibody (clone 9D5-9F3-8H1) | IHC | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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