Recombinant Mouse Anti-Mouse J1 Antibody (M2139) (CAT#: PABL-649)

Recombinant Mouse Antibody (M2139) is capable of binding to Mouse J1 , expressed in Chinese Hamster Ovary cells (CHO). This mAb specifically recognizes the J1 epitope and is the most arthritogenic anti-CII mAb in the mouse, eliciting disease upon single transfer.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA

Figure 1 Western blot analysis antibody M2139 binding to recombinant IdeS.

Figure 1 Western blot analysis antibody M2139 binding to recombinant IdeS.

Recombinant IdeS was incubated with purified monoclonal antibody (mAb) M287 (IgG2a), CIIC1 (IgG2a), M2139 (IgG2b), M284 (IgG1), or B10 (IgG3), separated by sodium dodecyl sulfate–polyacrylamide gel electrophoresis under reducing conditions on Precise Protein Gradient Gels, and stained with Coomassie blue.

Nandakumar, K. S., Johansson, B. P., Björck, L., & Holmdahl, R. (2007). Blocking of experimental arthritis by cleavage of IgG antibodies in vivo. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology, 56(10), 3253-3260.


Specifications

  • Immunogen
  • Mouse collagen, type II, alpha 1
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • IgG
  • Specificity
  • Tested positive against native Mouse J1
  • Species Reactivity
  • Mouse
  • Clone
  • M2139
  • Applications
  • WB 1:1000-1:10000
    ELISA 1:1000-1:20000

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Applications

  • Application Notes
  • Assay-depended

Target

  • Alternative Names
  • COL2A1; collagen, type II, alpha 1; Dmm; Lpk; Col2; Del1; Col2a; Col2a-1; M100856; Rgsc856; collagen alpha-1(II) chain; chondrocalcin; alpha-1 type II collagen; disproportionate micromelia; procollagen, type II, alpha 1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone M2139"

See other products for "COL2A1"

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for PABL-649. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare