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    Anti-Human NTRK2 Recombinant Antibody (38B8) (CAT#: TAB-172CQ)

    The antibody is directed against TrkB and has an effect on body weight and food intake qualitatively similar to NT-4/5, a natural trkB agonist.

    Specific Inquiry
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    • Conjugation:

    • Endotoxin:

    • Purity:

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    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    ELISA

    Figure 2 CellSensorH TrkB-NFAT-bla CHO-K1 cells were stimulated with BDNF, mAb 38B8 and mAb 29D7 6 pan-Trk inhibitor (100 nM) over the indicated concentration range for 5 hours before b-lactamase assay.

    Figure 2 CellSensorH TrkB-NFAT-bla CHO-K1 cells were stimulated with BDNF, mAb 38B8 and mAb 29D7 6 pan-Trk inhibitor (100 nM) over the indicated concentration range for 5 hours before b-lactamase assay.

    Todd, D., Gowers, I., Dowler, S. J., Wall, M. D., McAllister, G., Fischer, D. F., ... & Flynn, G. (2014). A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington’s disease. PloS one,  9(2), e87923.


    Specifications

    • Immunogen
    • Human TrkB extracellular domain
    • Host Species
    • Mouse
    • Specificity
    • Human
    • Species Reactivity
    • Human, Rat, Mouse, Cynomolgus monkey
    • Clone
    • 38B8
    • Applications
    • ELISA, FC
    • Related Disease
    • Unwanted body weight loss and eating disorders

    Applications

    • Application Notes
    • This antibody has been tested for use in ELISA, Flow Cytometry. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

    Target

    • Alternative Names
    • NTRK2; Neurotrophic receptor tyrosine kinase 2; TRKB; trk-B; GP145-TrkB; BDNF/NT-3 growth factors receptor; tyrosine kinase receptor B; tropomyosin-related kinase B; BDNF-tropomyosine receptor kinase B

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    Mouse Antibody Products Humanized Antibody Products Human Antibody Products IgG Antibody Products Rabbit Monoclonal Antibody Products Neuroscience Antibody Products Fab Antibody Products ScFv Antibody Products ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    TAB-171CQ Anti-Human NTRK2 Recombinant Antibody (18H6) ELISA, FC
    TAB-173CQ Anti-Human NTRK2 Recombinant Antibody (6B72C5) ELISA, WB, IP
    TAB-174CQ Anti-Human NTRK2 Recombinant Antibody (5G5D2B5) FuncS, WB
    TAB-175CQ Anti-Human NTRK2 Recombinant Antibody (17D11) ELISA, FC, WB
    TAB-176CQ Anti-Human NTRK2 Recombinant Antibody (29D7) WB, IF, ELISA, FC

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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