Anti-Human NTRK2 Recombinant Antibody (38B8) (CAT#: TAB-172CQ)
The antibody is directed against TrkB and has an effect on body weight and food intake qualitatively similar to NT-4/5, a natural trkB agonist.
Specific Inquiry
ELISA
Figure 2 CellSensorH TrkB-NFAT-bla CHO-K1 cells were stimulated with BDNF, mAb 38B8 and mAb 29D7 6 pan-Trk inhibitor (100 nM) over the indicated concentration range for 5 hours before b-lactamase assay.
Todd, D., Gowers, I., Dowler, S. J., Wall, M. D., McAllister, G., Fischer, D. F., ... & Flynn, G. (2014). A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington’s disease. PloS one, 9(2), e87923.
Specifications
- Immunogen
- Human TrkB extracellular domain
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human, Rat, Mouse, Cynomolgus monkey
- Clone
- 38B8
- Applications
- ELISA, FC
- Related Disease
- Unwanted body weight loss and eating disorders
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Flow Cytometry. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- NTRK2; Neurotrophic receptor tyrosine kinase 2; TRKB; trk-B; GP145-TrkB; BDNF/NT-3 growth factors receptor; tyrosine kinase receptor B; tropomyosin-related kinase B; BDNF-tropomyosine receptor kinase B
- Gene ID
- 4915
- UniProt ID
- Q16620
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2510z | Mouse Anti-NTRK2 Recombinant Antibody (clone 20A1) | WB, ICC, IF, IHC | Mouse IgG1 |
| HPAB-N0197-YC | Mouse Anti-NTRK2 Recombinant Antibody (HPAB-N0197-YC) | FuncS, WB | Mouse IgG |
| HPAB-N0198-YC | Mouse Anti-NTRK2 Recombinant Antibody (HPAB-N0198-YC) | FuncS | Mouse IgG |
| HPAB-N0199-YC | Mouse Anti-NTRK2 Recombinant Antibody (HPAB-N0199-YC) | FuncS | Mouse IgG |
| HPAB-N0200-YC | Human Anti-NTRK2 Recombinant Antibody (HPAB-N0200-YC) | FuncS, WB | Humanized IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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