Anti-Human NTRK2 Recombinant Antibody (6B72C5)

Name: Anti-Human NTRK2 Recombinant Antibody (6B72C5)
SKU: TAB-173CQ
Rating: 5 (1 reviews)

CAT#: TAB-173CQ

The monoclonal antibody binds to a particular part of tropomyosin-related kinase B receptor (TrkB) and can be potentially used in the treatment of cancer, pain, anorexia, anorexia nervosa and cachexia.

Published Data Gene Expression

ELISA

Figure 1 Inhibition ELISA confirmed the specificity of the bind ing for B1 peptide and TrkB.

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Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7637/202_C1_1_selected.jpg

Normal Tissue Figure 2 High expression in cerebral cortex

Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_B_7_5.jpg

Normal Tissue Figure 3 Kidney

Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_A_8_5.jpg

Normal Tissue Figure 4 Testis

Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10346/162989_A_6_6.jpg

RNA Expression Figure 5 RNA cell line category: Cell line enhanced (AF22, HaCaT, RPTEC TERT1, SH-SY5Y, SuSa)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148053-NTRK2

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Specifications

Immunogen
A peptide corresponding to the first loop of the D5 domain of the TrkB(B1 peptide, TITFLESPTSDHHWCIPFTV)

Host Species
Rat

Specificity
Human

Species Reactivity
Human

Clone
6B72C5

Applications
ELISA, WB, IP

Related Disease
Cancer

Applications

Application Notes
This antibody has been tested for use in ELISA, Western Blot, Immunoprecipitation. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

Target

Alternative Names
NTRK2; Neurotrophic receptor tyrosine kinase 2; TRKB; trk-B; GP145-TrkB; BDNF/NT-3 growth factors receptor; tyrosine kinase receptor B; tropomyosin-related kinase B; BDNF-tropomyosine receptor kinase B

Gene ID
4915

UniProt ID
Q16620

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Related Diseases

EGFR Tyrosine Kinase Inhibitor Resistance

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-173CQ.pdf

MSDS

MSDS - TAB-173CQ.pdf

COA

Certificate of Analysis Lookup

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