The monoclonal antibody recognizes loop-3 of the IgG-1 segment of human TrkB (ENLVGED) and may also recognizes loop-1 of the IgG-1 segment of human TrkB (AGDPVP) and blocks caspase-3 activation caused by hypoxic-ischemic (HI) injury.
Figure 1 29D7 increases phosphorylation of ERK1/2 and AKT in vivo.
Kim, G. S., Cho, S., Nelson, J. W., Zipfel, G. J., & Han, B. H. (2014). TrkB agonist antibody pretreatment enhances neuronal survival and long-term sensory motor function following hypoxic ischemic injury in neonatal rats. PloS one, 9(2), e88962.
Figure 2 29D7 induces phosphorylation of ERK1/2 in neurons.
Coronally sectioned brain sections were immunofluorescently double-labeled with anti-phospho-ERK1/2 (pERK1/2) antibody (red) and a neuron-specific marker, NeuN (green), followed by fluorescent microscopy.
Kim, G. S., Cho, S., Nelson, J. W., Zipfel, G. J., & Han, B. H. (2014). TrkB agonist antibody pretreatment enhances neuronal survival and long-term sensory motor function following hypoxic ischemic injury in neonatal rats. PloS one, 9(2), e88962.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-180CQ | Anti-Human NTRK2 Recombinant Antibody (C20) | FuncS | Human antibody |
TAB-180CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (C20) | ELISA, FC, WB | Human antibody |
TAB-180CQ-F(E) | Anti-Human NTRK2 Recombinant Antibody Fab Fragment (C20) | ELISA, FC, WB | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-171CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (18H6) | ELISA, FC | |
TAB-172CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (38B8) | ELISA, FC | |
TAB-173CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (6B72C5) | ELISA, WB, IP | |
TAB-174CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (5G5D2B5) | ELISA, WB, IP | |
TAB-175CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (17D11) | ELISA, FC, WB |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-177CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (C2) | ELISA, FC | Humanized antibody |
TAB-178CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (A2) | ELISA, FC | Humanized antibody |
TAB-179CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (RN1026A) | ELISA, FC | Humanized antibody |
TAB-177CQ-F(E) | Anti-Human NTRK2 Recombinant Antibody Fab Fragment (C2) | ELISA, FC | Humanized antibody |
TAB-178CQ-F(E) | Anti-Human NTRK2 Recombinant Antibody Fab Fragment (A2) | ELISA, FC | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2509 | Hi-Affi™ Recombinant Rabbit Anti-NTRK2 Monoclonal Antibody (DS2509AB) | WB, IHC, IP | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-095CN | Human Anti-NTRK2 Recombinant Antibody (NS-095CN) | ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-095CN-F(E) | Human Anti-NTRK2 Recombinant Antibody; Fab Fragment (NS-095CN-F(E)) | ELISA | Human Fab |
HPAB-AP765-YC-F(E) | Human Anti-NTRK2 Recombinant Antibody (clone 4B12-15); Fab Fragment | Agonist | Humanized Fab |
HPAB-AP766-YC-F(E) | Human Anti-NTRK2 Recombinant Antibody (clone 4B12-27); Fab Fragment | Agonist | Humanized Fab |
HPAB-AP767-YC-F(E) | Human Anti-NTRK2 Recombinant Antibody (clone A6-10); Fab Fragment | Agonist | Humanized Fab |
HPAB-AP768-YC-F(E) | Human Anti-NTRK2 Recombinant Antibody (clone 1-A6); Fab Fragment | Agonist | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBC-458 | Mouse Anti-NTRK2 Recombinant Antibody (clone AB20); scFv Fragment | ELISA, FC, IF, Agonist | Mouse scFv |
HPAB-AP770-YC-S(P) | Human Anti-NTRK2 Recombinant Antibody (clone 1-B11); scFv Fragment | Agonist | Human scFv |
HPAB-AP771-YC-S(P) | Human Anti-NTRK2 Recombinant Antibody (clone 1-G12); scFv Fragment | Agonist | Human scFv |
HPAB-AP772-YC-S(P) | Human Anti-NTRK2 Recombinant Antibody (clone 2-A2); scFv Fragment | Agonist | Human scFv |
HPAB-AP773-YC-S(P) | Human Anti-NTRK2 Recombinant Antibody (clone 2-B1); scFv Fragment | Agonist | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-2391-CN | Recombinant Rabbit Anti-NTRK2 (phosphorylated Tyr817) Monoclonal Antibody (CBACN-676) | WB, IF, IHC, IP | Rabbit IgG |
HPAB-N0197-YC | Mouse Anti-NTRK2 Recombinant Antibody (HPAB-N0197-YC) | FuncS, WB | Mouse IgG |
HPAB-N0198-YC | Mouse Anti-NTRK2 Recombinant Antibody (HPAB-N0198-YC) | FuncS | Mouse IgG |
HPAB-N0199-YC | Mouse Anti-NTRK2 Recombinant Antibody (HPAB-N0199-YC) | FuncS | Mouse IgG |
HPAB-N0200-YC | Human Anti-NTRK2 Recombinant Antibody (HPAB-N0200-YC) | FuncS, WB | Humanized IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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