Human Anti-ROR1 Recombinant Antibody; Fab Fragment (TAB-343CT-F(E))
CAT#: TAB-343CT-F(E)
This product is a recombinant human antibody Fab fragment that recognizes ROR 1. The epitope is within the extracellular domain. The antibody bound effectively to the cell-surface human ROR1 expressed in A549, CALU1, H358, PANC-1, H226, H69 and HT-29 cells.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, CACO-2, HHSteC, HSkMC, NTERA-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185483-ROR1
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Specifications
- Immunogen
- Recombinant ROR1 antigen (the extracellular domain)
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human ROR 1
- Species Reactivity
- Human
- Applications
- Used for immunoassay techniques such as: Western Blot; Enzyme-linked Immunosorbent Assay; Flow Cytometry; Immunofluorescence; Blocking
- Related Disease
- Non-small cell lung carcinoma, B-cell chronic lymphocytic leukemia and colon cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Outstanding for Immunofluorescence
Utilizing this Fab fragment in immunofluorescence has delivered superior imaging results. Its small size ensures excellent tissue penetration and minimal background, a must-have for accurate localization studies.
Exceptional for ROR1 Targeting
Its specialized targeting of ROR1 has propelled our research forward, especially concerning therapeutic target validation. The Fab fragment supports our need for detailed and precise investigations into cancer cell markers.
Clarity in Western Blot Results
The antibody consistently delivers clear, distinct bands in Western blot assays, facilitating precise interpretation of ROR1 expression levels in our diverse research projects.
Q&As
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What are the research applications for this antibody?
A: This antibody is typically used in Western blot (WB), enzyme-linked immunosorbent assay (ELISA), flow cytometry (FC), and immunofluorescence (IF) to study protein expressions and functions.
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How does targeting ROR1 benefit cancer research?
A: ROR1 is implicated in various cancers, such as non-small cell lung carcinoma and B-cell chronic lymphocytic leukemia, making it a vital target for studying tumor progression and developing therapeutic strategies.
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Why is the Fab fragment suitable for immunofluorescence applications?
A: The smaller size of the Fab fragment allows for better tissue penetration and less steric hindrance during staining, resulting in clearer imaging for detailed studies.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "ROR1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-336CT | Mouse Anti-ROR1 Recombinant Antibody (TAB-336CT) | WB, ELISA, FC | Mouse IgG1 |
| TAB-337CT | Mouse Anti-ROR1 Recombinant Antibody (TAB-337CT) | WB, FC, Cyt | Mouse IgG1 |
| TAB-338CT | Mouse Anti-ROR1 Recombinant Antibody (TAB-338CT) | WB, FC, Cyt | Mouse IgG1 |
| TAB-336CT-F(E) | Mouse Anti-ROR1 Recombinant Antibody; Fab Fragment (TAB-336CT-F(E)) | WB, ELISA, FC | Mouse Fab |
| TAB-337CT-F(E) | Mouse Anti-ROR1 Recombinant Antibody; Fab Fragment (TAB-337CT-F(E)) | WB, ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-339CT | Human Anti-ROR1 Recombinant Antibody (TAB-339CT) | WB, ELISA, FC | Human antibody |
| TAB-340CT | Human Anti-ROR1 Recombinant Antibody (TAB-340CT) | WB, ELISA, FC | Human antibody |
| TAB-341CT | Human Anti-ROR1 Recombinant Antibody (TAB-341CT) | WB, ELISA, FC, IF, BL | Human IgG |
| TAB-342CT | Human Anti-ROR1 Recombinant Antibody (TAB-342CT) | WB, ELISA, FC, IF, BL | Human IgG |
| TAB-343CT | Human Anti-ROR1 Recombinant Antibody (TAB-343CT) | WB, ELISA, FC, IF, BL | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0220-CN-S(P) | Human Anti-ROR1 Recombinant Antibody; scFv Fragment (HPAB-0220-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0221-CN-S(P) | Human Anti-ROR1 Recombinant Antibody; scFv Fragment (HPAB-0221-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0222-CN-S(P) | Human Anti-ROR1 Recombinant Antibody; scFv Fragment (HPAB-0222-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0566LY-S(P) | Human Anti-ROR1 Recombinant Antibody scFv Fragment (HPAB-0566LY-S(P)) | ELISA, RIA, FC, Inhib, WB | Humanized scfv |
| HPAB-0567LY-S(P) | Human Anti-ROR1 Recombinant Antibody scFv Fragment (HPAB-0567LY-S(P)) | ELISA, RIA, FC, Inhib, WB | Humanized scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0566LY | Human Anti-ROR1 Recombinant Antibody (HPAB-0566LY) | ELISA, RIA, FC, Inhib, WB | Humanized IgG1 |
| HPAB-0567LY | Human Anti-ROR1 Recombinant Antibody (HPAB-0567LY) | ELISA, RIA, FC, Inhib, WB | Humanized IgG1 |
| HPAB-0568LY | Human Anti-ROR1 Recombinant Antibody (HPAB-0568LY) | ELISA, RIA, FC, Inhib, WB | Humanized IgG1 |
| HPAB-0569LY | Human Anti-ROR1 Recombinant Antibody (HPAB-0569LY) | ELISA, RIA, FC, Inhib, WB | Humanized IgG1 |
| HPAB-0570LY | Human Anti-ROR1 Recombinant Antibody (HPAB-0570LY) | ELISA, RIA, FC, Inhib, WB | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0566LY-F(E) | Human Anti-ROR1 Recombinant Antibody Fab Fragment (HPAB-0566LY-F(E)) | ELISA, RIA, FC, Inhib, WB | Humanized Fab |
| HPAB-0567LY-F(E) | Human Anti-ROR1 Recombinant Antibody Fab Fragment (HPAB-0567LY-F(E)) | ELISA, RIA, FC, Inhib, WB | Humanized Fab |
| HPAB-0568LY-F(E) | Human Anti-ROR1 Recombinant Antibody Fab Fragment (HPAB-0568LY-F(E)) | ELISA, RIA, FC, Inhib, WB | Humanized Fab |
| HPAB-0569LY-F(E) | Human Anti-ROR1 Recombinant Antibody Fab Fragment (HPAB-0569LY-F(E)) | ELISA, RIA, FC, Inhib, WB | Humanized Fab |
| HPAB-0570LY-F(E) | Human Anti-ROR1 Recombinant Antibody Fab Fragment (HPAB-0570LY-F(E)) | ELISA, RIA, FC, Inhib, WB | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC148 | Human Anti-ROR1 Recombinant Antibody Hexamer (VS-0924-YC148), CDC Enhanced | ELISA, SPR, FC, ADCC, CDC | Antibody hexamer |
| VS-0924-YC149 | Mouse Anti-ROR1 Recombinant Antibody Hexamer (VS-0924-YC149), CDC Enhanced | ELISA, FC, CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY36 | Human Anti-ROR1 scFv-Fc Chimera (VS-0125-FY36) | ADCC, CDC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1937 | Anti-ROR1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC619 | Recombinant Anti-ROR1 Vesicular Antibody, EV Displayed (VS-0425-YC619) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC155 | Recombinant Anti-ROR1 (AA 132-153 x AA 904-918) Biparatopic Antibody, Tandem scFv | ELISA, FC | Tandem scFv |
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