Afuco™ Anti-Human SELPLG ADCC Recombinant Antibody (AbGn-168), ADCC Enhanced

CAT#: AFC-533CL

Anti-SELPLG ADCC Enhanced Antibody (AbGn-168) is an ADCC enhanced antibody produced by our Afuco™ platform. AbGn-168H is a humanized monoclonal antibody being developed to treat inflammatory diseases, has been demonstrated in a randomized, multicenter, double-blind, placebo-controlled phase II trial in patients with moderate-to-severe plaque psoriasis. Due to the unique mechanism of action, AbGn-168H has potential benefit for treating multiple immune-related diseases.

Gene Expression
Figure 1 IF staining of human cell line HEL Figure 2 High expression in spleen. Figure 3 Kidney Figure 4 Lymph node Figure 5 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, JURKAT, Karpas-707, RPMI-8226, U-266/70, U-266/84)

Specifications

  • Host Species
  • Humanized
  • Derivation
  • Humanized
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Autoimmune Diseases; Cancer; Psoriasis

Product Property

  • Purity
  • >95% (SDS-PAGE)
  • Storage
  • Store at –20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.

Target

  • Alternative Names
  • SELPLG; selectin P ligand; CLA; CD162; PSGL1; PSGL-1; P-selectin glycoprotein ligand 1; cutaneous lymphocyte-associated associated antigen
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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