Anti-SLAMF7 Recombinant Antibody (Elotuzumab) (CAT#: TAB-743)
Recombinant humanized antibody expressed in CHO binding to human SLAMF7/CD319. Elotuzumab is a humanized monoclonal antibody which is under phase III clinical investigation in relapsed multiple myeloma.
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ELISA
Figure 1 Anti-SLAMF7 Recombinant Antibody (TAB-743) in ELISA
ELISA analysis of TAB-743 was performed by coating with SLAMF7 antigen. The HRP-conjugated goat anti-human IgG was used as a secondary antibody.
WB
Figure 2 Anti-SLAMF7 Recombinant Antibody (TAB-743) in WB
Western blot analysis of TAB-743 was performed with 3 µg onto a 12% Tris-HCl polyacrylamide gel in β-mercaptoethanol-reduced (Lane 1) conditions. Goat Anti-Human IgG HRP secondary antibody at a dilution of 1:8,000 for 75 minutes.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG1 - kappa
- Species Reactivity
- Human
- Applications
- Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, IHC and most other immunological methods.
- CAS
- 915296-00-3
- Generic Name
- elotuzumab
- UNII
- 1351PE5UGS
- MW
- 145.5 kDa
- Related Disease
- Multiple myeloma (MM)
Product Property
- Purity
- >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- Store at -20°C. Avoid multiple freeze/thaw cycles.
Target
- Alternative Names
- elotuzumab;915296-00-3;HuLuc63;PDL063;PDL-063;BMS-901608;HuLuc63;SLAMF7;SLAM family member 7;19A;CD319;CRACC;CS1;protein 19A;CD2 subset 1;19A24 protein;membrane protein FOAP-12;CD2-like receptor activating cytotoxic cells;CD2-like receptor-activating cyto
- Gene ID
- 57823
- UniProt ID
- Q9NQ25
Related Resources
Please refer to Elotuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Elotuzumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Elotuzumab"
Afuco™ Anti-SLAMF7 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-743)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized antibody expressed in CHO binding to human SLAMF7/CD319. It is a humanized monoclonal antibody which is under phase III clinical investigation in relapsed multiple myeloma.
DrugMonitor™ Anti-Elotuzumab Antibody (VS-1224-YC413)Elotuzumab is a humanized IgG1 monoclonal antibody indicated for use with lenalidomide and dexamethasone in multiple myeloma treatment. The DrugMonitor™ Anti-Elotuzumab Antibody (VS-1224-YC413) is an anti-drug antibody (ADA) against Elotuzumab. This drug-based antibody is raised in mice immunized with the Elotuzumab. The anti-Elotuzumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Elotuzumab in samples.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1881z | Mouse Anti-SLAMF7 Recombinant Antibody (clone 4C10) | WB, IHC | Mouse IgG1 |
| VS3-WK1 | Rabbit Anti-SLAMF7 Recombinant Antibody (clone DM10) | ELISA, FC, IP, IF | Rabbit IgG |
| VS3-WK2 | Rabbit Anti-SLAMF7 Recombinant Antibody (clone DM11) | ELISA, FC, IP, IF | Rabbit IgG |
| VS-0224-XY118 | Mouse Anti-SLAMF7 Recombinant Antibody (VS-0224-XY118), PE | FC | Mouse IgG2b |
| VS13-YC1062 | Rabbit Anti-SLAMF7 Recombinant Antibody (VS13-YC1062) | IHC-P | Rabbit IgG |
Customer Reviews and Q&As
Customer Review
Q&As
Robust Performance in Myeloma Research
Using Elotuzumab in our research has greatly enhanced our understanding of immune mechanisms in multiple myeloma. Its precise targeting of SLAMF7/CD319 has been invaluable in advancing our therapeutic approaches.
Versatile and Effective
This antibody has shown remarkable versatility across different assays, from ELISA to flow cytometry, consistently delivering high-quality data that underpins our cancer research projects.
Reliable in Experimental Applications
The antibody's reliability has been proven time and again in immunoprecipitation and functional assays, reinforcing its role as a reliable tool in our immunological research.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-743, RRID: AB_3111998)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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