Afuco™ Anti-Human TFPI ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-580CL
Anti-TFPI ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The monoclonal antibodies that bind human tissue factor pathway inhibitor (TFPI) are used for treatment of genetic and acquired deficiencies or defects in coagulation such as hemophilia A and B.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human smooth muscle
Immunohistochemical staining of human smooth muscle shows distinct positivity in endothelial.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5575/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows distinct cytoplasmic positivity in endothelium.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Endocrine cells Staining: High Intensity: Strong Endothelial cells Staining: High Intensity: Strong Quantity:>75% Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25% Peripheral nerve/ganglion Staining: Low Intensity: Weak
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_7_3.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_4_6.jpg
Normal Tissue
Figure 6 Placenta
Decidual cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_2_7.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HHSteC, HUVEC TERT2, LHCN-M2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000003436-TFPI
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Hemophilia
Product Property
- Purity
- 95% by HPLC
- Storage
- 4 °C, -20°C if preferred
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "TFPI"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-734 | Anti-TFPI Recombinant Antibody (Concizumab) | ELISA, IP, FC, FuncS, Neut, IF, WB | IgG4 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-711 | Human Anti-TFPI Recombinant Antibody (clone mAb 2021); scFv Fragment | Block | Human scFv |
| HPAB-0488-CN-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0488-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0489-CN-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0489-CN-S(P)) | ELISA, FC | Human scFv |
| PSBC-539 | Human Anti-TFPI Recombinant Antibody (clone ch2F22); scFv Fragment | ELISA, FC, Neut | Mouse scFv |
| HPAB-2597LY-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-2597LY-S(P)) | ELISA, WB, FuncS | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3547 | Rabbit Anti-TFPI Recombinant Antibody (clone DS3547AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0476-CN-F(E) | Mouse Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0476-CN-F(E)) | ELISA | Mouse Fab |
| HPAB-0477-CN-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0477-CN-F(E)) | ELISA, Neut | Human Fab |
| HPAB-0478-CN-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0478-CN-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0479-CN-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0479-CN-F(E)) | ELISA, Neut | Human Fab |
| HPAB-0480-CN-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0480-CN-F(E)) | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-734 | Afuco™ Anti-TFPI ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-734) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2598LY | Human Anti-TFPI Recombinant Antibody (HPAB-2598LY) | ELISA, WB, FuncS | Human IgG |
| HPAB-2599LY | Human Anti-TFPI Recombinant Antibody (HPAB-2599LY) | ELISA, WB, FuncS | Human IgG |
| HPAB-2600LY | Human Anti-TFPI Recombinant Antibody (HPAB-2600LY) | ELISA, WB, FuncS | Human IgG |
| HPAB-2601LY | Human Anti-TFPI Recombinant Antibody (HPAB-2601LY) | ELISA, WB, FuncS | Human IgG |
| HPAB-2602LY | Human Anti-TFPI Recombinant Antibody (HPAB-2602LY) | ELISA, WB, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC647 | AbPlus™ Anti-TFPI Magnetic Beads (VS-0724-YC647) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY189 | Human Anti-TFPI (clone Concizumab) scFv-Fc Chimera | ELISA, FC | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7198 | Anti-TFPI Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC305 | Recombinant Anti-TFPI Eliminating Antibody, pH-Sensitive (VS-0625-YC305) | Antigen-Sweeping In Vivo. | Human IgG4 kappa |
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