Human Anti-TFPI Recombinant Antibody (clone TFPI-106)
CAT#: HPAB-0428-YC
Provided are antibodies that specifically bind TFPI and inhibit an activity thereof. Such antibodies are useful for treating bleeding disorders and shortening clotting time.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human smooth muscle
Immunohistochemical staining of human smooth muscle shows distinct positivity in endothelial.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5575/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows distinct cytoplasmic positivity in endothelium.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Endocrine cells Staining: High Intensity: Strong Endothelial cells Staining: High Intensity: Strong Quantity:>75% Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25% Peripheral nerve/ganglion Staining: Low Intensity: Weak
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_7_3.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_4_6.jpg
Normal Tissue
Figure 6 Placenta
Decidual cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_2_7.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HHSteC, HUVEC TERT2, LHCN-M2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000003436-TFPI
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Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human IgG
- Specificity
- Human TFPI
- Species Reactivity
- Human, Mouse, Rabbit, Rat, Cynomolgus
- Clone
- TFPI-106
- Applications
- ELISA, FC, FuncS
- Related Disease
- Bleeding disorder, Shortening clotting time
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Flow Cytometry, Functional Assay.
Target
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Efficient in ELISA Assays
We have employed this antibody in multiple ELISA assays, and it has consistently provided us with precise and reliable results, offering clarity in our evaluations of TFPI levels in our biological samples.
Versatile Applications
We appreciate the versatility of this antibody. It's proven effective in functional studies and ELISA, helping us delve deeper into coagulation pathways with confidence in its binding accuracy.
Impactful in Functional Assays
In functional assays related to bleeding disorders, the antibody demonstrated its potential by helping us visualize and quantify TFPI effectively, contributing valuable insights to our studies.
Q&As
-
Which applications is this antibody suitable for?
A: This antibody is suitable for ELISA, flow cytometry (FC), and functional studies (FuncS). Researchers can use it to analyze the presence and activity of TFPI in various samples.
-
Is it possible to use this antibody with multiple species?
A: Yes, the Human Anti-TFPI Recombinant Antibody is tested for reactivity with human, mouse, rabbit, rat, and cynomolgus samples, making it useful across various experimental models.
-
What gene does TFPI relate to?
A: TFPI relates to the gene encoding tissue factor pathway inhibitor, which plays a critical role in controlling blood coagulation. Its UniProt ID is P10646.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone TFPI-106"
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-734 | Anti-TFPI Recombinant Antibody (Concizumab) | ELISA, IP, FC, FuncS, Neut, IF, WB | IgG4 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-718 | Human Anti-TFPI Recombinant Antibody (clone mAb 2021) | Block | Human IgG |
| MOB-0374MZ | Recombinant Mouse Anti-Human Tissue Factor Pathway Inhibitor Antibody (clone BIUGQJ-5139) | RIA, WB, ELISA | Mouse antibody |
| MOB-2015CT | Recombinant Mouse anti-Human TFPI Monoclonal antibody (5H5) | ELISA, WB | |
| HPAB-0429-YC | Human Anti-TFPI Recombinant Antibody (clone TFPI-118) | ELISA, FC, FuncS | Human IgG |
| HPAB-0431-YC | Human Anti-TFPI Recombinant Antibody (HPAB-0431-YC) | ELISA, FC, FuncS | Chimeric (mouse/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-711 | Human Anti-TFPI Recombinant Antibody (clone mAb 2021); Fab Fragment | Block | Human Fab |
| HPAB-0476-CN-F(E) | Mouse Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0476-CN-F(E)) | ELISA | Mouse Fab |
| HPAB-0477-CN-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0477-CN-F(E)) | ELISA, Neut | Human Fab |
| HPAB-0478-CN-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0478-CN-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0479-CN-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0479-CN-F(E)) | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3547 | Rabbit Anti-TFPI Recombinant Antibody (clone DS3547AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0476-CN-S(P) | Mouse Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0476-CN-S(P)) | ELISA | Mouse scFv |
| HPAB-0477-CN-S(P) | Mouse Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0477-CN-S(P)) | ELISA, Neut | Mouse scFv |
| HPAB-0478-CN-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0478-CN-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0479-CN-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0479-CN-S(P)) | ELISA, Neut | Human scFv |
| HPAB-0480-CN-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0480-CN-S(P)) | ELISA, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-734 | Afuco™ Anti-TFPI ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-734) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC647 | AbPlus™ Anti-TFPI Magnetic Beads (VS-0724-YC647) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY189 | Human Anti-TFPI (clone Concizumab) scFv-Fc Chimera | ELISA, FC | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7198 | Anti-TFPI Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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