Rat Anti-Tnfsf11 Recombinant Antibody (clone IK22/5) (CAT#: NEUT-2178CQ)
This antibody is a rat monoclonal antibody that binds specifically to mouse RANKL, and it can neutralize the bioactivity of mouse RANKL.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in lymph node
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45142/ihc_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45142/ihc_selected.jpg
Figure 2 Low expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45142/114242_B_7_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45142/114242_B_7_5_val_selected.jpg
Figure 3 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows moderate positivity in hematopoietic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9193/ihc_selected.jpg
(Immunohistochemical staining of human bone marrow shows moderate positivity in hematopoietic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9193/ihc_selected.jpg
Figure 4 Lymph node
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45142/114242_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45142/114242_A_8_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (HSkMC, NTERA-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120659-TNFSF11
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120659-TNFSF11
Specifications
- Immunogen
- NSO derived Recombinant mouse TRANCE.
- Host Species
- Rat
- Type
- Rat IgG2a, κ
- Specificity
- Mouse Tnfsf11
- Species Reactivity
- Mouse
- Clone
- IK22/5
- Applications
- Block, FC, IP, WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Tnfsf11; tumor necrosis factor (ligand) superfamily, member 11; ODF; OPGL; RANKL; Ly109l; Trance
- Gene ID
- 21943
- UniProt ID
- O35235
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TNFSF11"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1441z | Mouse Anti-TNFSF11 Recombinant Antibody (clone 27H11) | WB, ELISA, FC, IHC | Mouse IgG1 |
| MOB-1773CT | Recombinant Mouse anti-Mouse TNFSF11 Monoclonal antibody (23B779) | IHC-FoFr, WB | |
| HPAB-0072-YJ | Mouse Anti-TNFSF11 Recombinant Antibody (clone 2A4) | IA, ELISA, Neut | Mouse IgG2a, κ |
| HPAB-0075-YJ | Mouse Anti-TNFSF11 Recombinant Antibody (clone 19H22) | ELISA | Mouse IgG2b, κ |
| HPAB-0404-YJ | Rabbit Anti-TNFSF11 Recombinant Antibody (HPAB-0404-YJ) | ELISA, FC, Neut, Inhib, FuncS | Rabbit IgG2, κ |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-310CT | Anti-Human RANKL Recombinant Antibody | ELISA, FC, Neut | |
| TAB-310CT-S(P) | Anti-Human RANKL Recombinant Antibody scFv Fragment | ELISA, FC, Neut | |
| TAB-310CT-F(E) | Anti-Human RANKL Recombinant Antibody Fab Fragment | ELISA, FC, Neut |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-299CT-S(P) | Anti-Human RANKL Recombinant Antibody scFv Fragment (RL1) | ELISA | Human antibody |
| TAB-300CT-S(P) | Anti-Human RANKL Recombinant Antibody scFv Fragment (RL2) | ELISA | Human antibody |
| TAB-301CT-S(P) | Anti-Human RANKL Recombinant Antibody scFv Fragment (RL3) | ELISA | Human antibody |
| TAB-302CT-S(P) | Anti-Human RANKL Recombinant Antibody scFv Fragment (RL4) | ELISA | Human antibody |
| TAB-303CT-S(P) | Anti-Human RANKL Recombinant Antibody scFv Fragment (RL5) | ELISA | Human antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2179CQ | Mouse Anti-TNFSF11 Recombinant Antibody (clone CBL188) | IHC, Neut, WB | Mouse IgG2 |
| NEUT-2180CQ | Mouse Anti-TNFSF11 Recombinant Antibody (clone CBL488) | IHC, Neut | Mouse IgG2b |
| NEUT-2181CQ | Mouse Anti-TNFSF11 Recombinant Antibody (clone CBL578) | Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3619 | Rabbit Anti-TNFSF11 Recombinant Antibody (clone DS3619AB) | WB, ICC, IP | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0727LY-S(P) | Mouse Anti-TNFSF11 Recombinant Antibody; scFv Fragment (HPAB-0727LY-S(P)) | IHC, ICC, FC, WB, ELISA | Mouse scfv |
| HPAB-AP836-YC-S(P) | Mouse Anti-TNFSF11 Recombinant Antibody (clone 4E4); scFv Fragment | Inhib, FuncS | Mouse scFv |
| HPAB-AP837-YC-S(P) | Mouse Anti-TNFSF11 Recombinant Antibody (clone 4F4); scFv Fragment | Inhib, FuncS | Mouse scFv |
| HPAB-AP838-YC-S(P) | Mouse Anti-TNFSF11 Recombinant Antibody (clone 4G6); scFv Fragment | Inhib, FuncS | Mouse scFv |
| HPAB-1927-FY-F(E) | Human Anti-TNFSF11 Recombinant Antibody (clone 2D8); scFv Fragment | IP, ELISA | Human scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H18 | Afuco™ Anti-TNFSF11 Recombinant Antibody (AFC-TAB-H18), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | Human IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0072-YJ-F(E) | Mouse Anti-TNFSF11 Recombinant Antibody (clone 2A4); Fab Fragment | IA, ELISA, Neut | Mouse Fab |
| HPAB-0075-YJ-F(E) | Mouse Anti-TNFSF11 Recombinant Antibody (clone 19H22); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0334-YJ-F(E) | Human Anti-TNFSF11 Recombinant Antibody (clone BA05-1); Fab Fragment | ELISA, FC, Block, Inhib, FuncS | Human Fab |
| HPAB-0335-YJ-F(E) | Human Anti-TNFSF11 Recombinant Antibody (clone BA05-2); Fab Fragment | ELISA, FC, Block, Inhib, FuncS | Human Fab |
| HPAB-0404-YJ-F(E) | Rabbit Anti-TNFSF11 Recombinant Antibody; Fab Fragment (HPAB-0404-YJ-F(E)) | ELISA, FC, Neut, Inhib, FuncS | Rabbit Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0313-YC | Human Anti-TNFSF11 Recombinant Single Domain Antibody (HPAB-J0313-YC) | ELISA, Block | Human VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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