Afuco™ Anti-TNFSF11 Recombinant Antibody (AFC-TAB-H18), ADCC Enhanced
CAT#: AFC-TAB-H18
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant human antibody to Human TNFSF11.
Gene Expression
Normal Tissue
Figure 1 High expression in lymph node
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45142/ihc_selected.jpg
Normal Tissue
Figure 2 Low expression in cerebral cortex
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45142/114242_B_7_5_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human bone marrow
Immunohistochemical staining of human bone marrow shows moderate positivity in hematopoietic cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9193/ihc_selected.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45142/114242_A_8_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HSkMC, NTERA-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120659-TNFSF11
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Specifications
- Host Species
- Human
- Derivation
- human
- Type
- Human IgG1
- Specificity
- TNFSF11 (tumor necrosis factor (TNF) superfamily member 11, osteoclast differentiation factor, ODF, OPGL, RANKL, TRANCE, CD254) [Homo sapiens]
- Species Reactivity
- Human
- Applications
- Neut, ELISA, IF, IP, FuncS, FC
- Conjugate
- Unconjugated
- Related Disease
- Postmenopausal women osteoporosis
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2178CQ | Rat Anti-Tnfsf11 Recombinant Antibody (clone IK22/5) | Block, FC, IP, WB | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2179CQ | Mouse Anti-TNFSF11 Recombinant Antibody (clone CBL188) | IHC, Neut, WB | Mouse IgG2 |
| NEUT-2180CQ | Mouse Anti-TNFSF11 Recombinant Antibody (clone CBL488) | IHC, Neut | Mouse IgG2b |
| NEUT-2181CQ | Mouse Anti-TNFSF11 Recombinant Antibody (clone CBL578) | Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3619 | Rabbit Anti-TNFSF11 Recombinant Antibody (clone DS3619AB) | WB, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0283-YC | Human Anti-TNFSF11 Recombinant Antibody (clone Omut-10) | ELISA | Human IgG |
| HPAB-N0284-YC | Human Anti-TNFSF11 Recombinant Antibody (HPAB-N0284-YC) | ELISA, Neut, Inhib | Humanized IgG |
| HPAB-N0285-YC | Mouse Anti-TNFSF11 Recombinant Antibody (HPAB-N0285-YC) | Neut, FuncS | Mouse IgG |
| HPAB-0334-YJ | Human Anti-TNFSF11 Recombinant Antibody (clone BA05-1) | ELISA, FC, Block, FuncS | Human IgG4, κ |
| HPAB-1186WJ | Mouse Anti-TNFSF11 Recombinant Antibody (clone 14F3) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0334-YJ-S(P) | Human Anti-TNFSF11 Recombinant Antibody (clone BA05-1); scFv Fragment | ELISA, FC, Block, Inhib, FuncS | Human scFv |
| HPAB-0335-YJ-S(P) | Human Anti-TNFSF11 Recombinant Antibody (clone BA05-2); scFv Fragment | ELISA, FC, Block, Inhib, FuncS | Human scFv |
| HPAB-0574-FY-S(P) | Human Anti-TNFSF11 Recombinant Antibody; scFv Fragment (HPAB-0574-FY-S(P)) | ELISA | Humanized scFv |
| HPAB-0575-FY-S(P) | Mouse Anti-TNFSF11 Recombinant Antibody; scFv Fragment (HPAB-0575-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-1619-FY-F(E) | Human Anti-TNFSF11 Recombinant Antibody; Fab Fragment (HPAB-1619-FY-F(E)) | Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0404-YJ-F(E) | Rabbit Anti-TNFSF11 Recombinant Antibody; Fab Fragment (HPAB-0404-YJ-F(E)) | ELISA, FC, Neut, Inhib, FuncS | Rabbit Fab |
| HPAB-0405-YJ-F(E) | Human Anti-TNFSF11 Recombinant Antibody; Fab Fragment (HPAB-0405-YJ-F(E)) | ELISA, FC, Neut, Inhib, FuncS | Humanized Fab |
| HPAB-0406-YJ-F(E) | Rabbit Anti-TNFSF11 Recombinant Antibody; Fab Fragment (HPAB-0406-YJ-F(E)) | ELISA, FC, Neut, Inhib, FuncS | Rabbit Fab |
| HPAB-0407-YJ-F(E) | Human Anti-TNFSF11 Recombinant Antibody; Fab Fragment (HPAB-0407-YJ-F(E)) | ELISA, FC, Neut, Inhib, FuncS | Humanized Fab |
| HPAB-AP830-YC-F(E) | Mouse Anti-TNFSF11 Recombinant Antibody (clone FLG5); Fab Fragment | Inhib, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0313-YC | Human Anti-TNFSF11 Recombinant Single Domain Antibody (HPAB-J0313-YC) | ELISA, Block | Human VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY258 | AbPlus™ Anti-TNFSF11 Magnetic Beads (VS-0424-XY258) | IP, Protein Purification | |
| VS-0724-YC1276 | AbPlus™ Anti-TNFSF11 Magnetic Beads (VS-0724-YC1276) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY171 | Human Anti-TNFSF11 scFv-Fc Chimera (VS-0425-FY171) | ELISA | Human IgG2, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC646 | Recombinant Anti-TNFSF11 Vesicular Antibody, EV Displayed (VS-0425-YC646) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7388 | Anti-TNFSF11 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7389 | Anti-Mouse TNFSF11 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7390 | Anti-Human TNFSF11 Immunohistochemistry Kit | IHC |
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