Recombinant Human Anti-VEGF Antibody (Fab-12)
CAT#: PABX-185
Anti-VEGF antibody is a Chimeric antibody (mouse/human) of IgG1 κ class that binds to an VEGF.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human VEGF
- Species Reactivity
- Human
- Clone
- Fab-12
- Applications
- ELISA Assay-Dependent
FuncS Assay-Dependent
Block Assay-Dependent
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- The antibody Fab-12 has been reported in applications of ELISA, FuncS, Block. It's recommended that the optimal antibody concentration, dilution, incubition time etc. are best to be carefully titrated in specific assays.
Target
- Alternative Names
- VEGF; Vascular endothelial growth factor; EPI0030; BD0801; Sevacizumab
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Great for VEGF-related experiments
The Recombinant Human Anti-VEGF Antibody (Fab-12) has significantly improved the accuracy of our angiogenesis assays. Its high affinity and specificity make it indispensable for our VEGF-related experiments. Highly recommended!
Helpful for studies on diabetic retinopathy
We are using this antibody for in vitro studies on diabetic retinopathy. The specificity and inhibition of the VEGF pathways we've observed have been highly insightful. This antibody is fundamental to our project
High affinity
The Recombinant Human Anti-VEGF Antibody (Fab-12) stands out for its high affinity, versatility in applications, and robust performance in both in vitro and in vivo models. It offers superior specificity and sensitivity compared to many commercially available VEGF antibodies.
Q&As
-
What is the action mechanism of the Recombinant Human Anti-VEGF Antibody (Fab-12)?
A: The mechanism involves specific binding to VEGF, which prevents VEGF from interacting with its receptors (VEGFR-1 and VEGFR-2) on the cell surface. This inhibition disrupts the downstream signaling involved in angiogenesis, thereby impeding new blood vessel formation.
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Can the Recombinant Human Anti-VEGF Antibody (Fab-12) be used in vivo studies?
A: Yes, the Recombinant Human Anti-VEGF Antibody (Fab-12) has been tested and validated for in vivo studies. Its stability and efficacy in animal models have shown promising results in reducing angiogenesis-related disorders, such as tumor growth and diabetic retinopathy.
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What is the recommended concentration for using the Recombinant Human Anti-VEGF Antibody (Fab-12) in ELISA?
A: For ELISA applications, a starting concentration of 1-2 µg/mL of the Recombinant Human Anti-VEGF Antibody (Fab-12) is recommended. This concentration can be optimized based on the specific requirements and sensitivity of the assay.
View the frequently asked questions answered by Creative Biolabs Support.
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Related Diseases
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone Fab-12"
- CAT
- Product Name
See other products for "VEGF"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-1036 | Recombinant Human Anti-VEGF Antibody | ELISA, WB, FC, FuncS | IgG |
| HPAB-0746LY | Human Anti-VEGF Recombinant Antibody (HPAB-0746LY) | ELISA | Humanized IgG1 |
| HPAB-AP213-YC | Human Anti-VEGF Recombinant Antibody (HPAB-AP213-YC) | ELISA | Human IgG |
| HPAB-J0264-YC | Human Anti-VEGF Recombinant Antibody (clone G12) | ELISA | Human IgG |
| HPAB-J0265-YC | Human Anti-VEGF Recombinant Antibody (clone E9) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-1036-F(E) | Recombinant Human Anti-VEGF Antibody Fab Fragment | ELISA, IF, FuncS | Fab |
| HPAB-0307LY-F(E) | Human Anti-VEGF Recombinant Antibody (clone XPA.10.072); Fab Fragment | ELISA, Inhib | Human Fab2 |
| HPAB-AP213-YC-F(E) | Human Anti-VEGF Recombinant Antibody; Fab Fragment (HPAB-AP213-YC-F(E)) | ELISA | Human Fab |
| HPAB-J0264-YC-F(E) | Human Anti-VEGF Recombinant Antibody (clone G12); Fab Fragment | ELISA, Neut | Human Fab |
| HPAB-J0265-YC-F(E) | Human Anti-VEGF Recombinant Antibody (clone E9); Fab Fragment | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-285CQ | Mouse Anti-VEGF Recombinant Antibody (TAB-285CQ) | ELISA, WB, Inhib | Mouse IgG1 |
| TAB-287CQ | Mouse Anti-VEGF Recombinant Antibody (TAB-287CQ) | ELISA | Mouse IgG1, κ |
| TAB-290CQ | Anti-Human VEGF Recombinant Antibody | ELISA, WB, Neut | |
| TAB-303CQ | Anti-Human VEGF Recombinant Antibody (TAB-303CQ) | ELISA, WB, Neut | |
| PABX-187 | Recombinant Mouse Anti-VEGF Antibody (YADS1) | WB, ELISA, Neut, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-288CQ | Human Anti-VEGF Recombinant Antibody (TAB-288CQ) | ELISA | Chimeric (Mouse/Human) IgG1, κ |
| TAB-301CQ | Human Anti-VEGF Recombinant Antibody (TAB-301CQ) | ELISA, FC, IHC, WB | Chimeric (Mouse/Human) IgG1, κ |
| TAB-288CQ-S(P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (TAB-288CQ-S(P)) | ELISA, WB, IHC, Block | Human scFv |
| TAB-301CQ-S(P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (TAB-301CQ-S(P)) | ELISA, FC, IHC, WB | Human scFv |
| TAB-288CQ-F(E) | Human Anti-VEGF Recombinant Antibody; Fab Fragment (TAB-288CQ-F(E)) | ELISA, WB, IHC, Block | Chimeric (Mouse/Human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-286CQ-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (BD2) | ELISA, WB, Neut | Human antibody |
| TAB-291CQ-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (3G6) | ELISA, Inhib | Human antibody |
| TAB-292CQ-F(E) | Human Anti-VEGF Recombinant Antibody; Fab Fragment (TAB-292CQ-F(E)) | ELISA, Inhib | Human Fab |
| TAB-296CQ-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (XPA.10.064) | ELISA, IHC, Inhib | Human antibody |
| TAB-297CQ-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (XPA.10.072) | ELISA, IHC, Inhib | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-289CQ-F(E) | Human Anti-VEGF Recombinant Antibody; Fab Fragment (TAB-289CQ-F(E)) | ELISA, WB, IHC, Block | Humanized Fab |
| TAB-293CQ-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (HAB1) | ELISA, Inhib | Humanized antibody |
| TAB-294CQ-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (hAB2) | ELISA, Inhib | Humanized antibody |
| TAB-295CQ-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (hAB3) | ELISA, Inhib | Humanized antibody |
| TAB-302CQ-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (TAB-302CQ-F(E)) | ELISA, WB, Neut | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-096LC | Recombinant Anti-Human VEGF Antibody (Fc glycosylation) | ELISA | Humanized antibody |
| Gly-143LC | Recombinant Anti-Human VEGF Antibody (Fc glycosylation) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-179LC | Recombinant Anti-Human VEGF Antibody (Non-glycosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4485 | Rabbit Anti-VEGF Recombinant Antibody (clone SI581DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2806LY-S(P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (HPAB-2806LY-S(P)) | ELISA, WB | Humanized scfv |
| HPAB-2807LY-S(P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (HPAB-2807LY-S(P)) | ELISA, WB | Humanized scfv |
| HPAB-2808LY-S(P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (HPAB-2808LY-S(P)) | ELISA, WB | Humanized scfv |
| HPAB-2809LY-S(P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (HPAB-2809LY-S(P)) | ELISA, WB | Humanized scfv |
| HPAB-2810LY-S(P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (HPAB-2810LY-S(P)) | ELISA, WB | Humanized scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0267-YC | Recombinant Camelid Anti-VEGF Single Domain Antibody (HPAB-J0267-YC) | ELISA, Neut | Camelid VHH |
| HPAB-J0268-YC | Recombinant Camelid Anti-VEGF Single Domain Antibody (HPAB-J0268-YC) | ELISA, Neut | Camelid VHH |
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