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Anti-VEGF Recombinant Antibody Products

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Anti-VEGF Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs leads the industry in biotechnological innovation, providing a superior range of anti-VEGF recombinant antibody products tailored for global research and therapeutic advancement. Our expertly designed antibodies deliver exceptional specificity and high affinity, enabling scientists worldwide to confidently pursue their critical investigations and accelerate drug discovery.

VEGF: A Pivotal Target for Angiogenesis-Related Therapies

Vascular Endothelial Growth Factor (VEGF) is a highly conserved signaling protein crucial for vasculogenesis and angiogenesis, playing a pivotal role in both physiological processes and various pathological conditions. Extensive research has elucidated its central involvement in tumor growth, metastasis, and ocular diseases like age-related macular degeneration (AMD) and diabetic retinopathy. Understanding and targeting VEGF pathways are therefore paramount for developing effective treatments for a wide range of angiogenesis-dependent diseases.

Alternative Names

Vascular endothelial growth factor; vascular permeability factor; VPF; MVCD1; L-VEGF.

Background

Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates vasculogenesis and angiogenesis. It is part of the system that restores the oxygen supply to tissues when blood circulation is inadequate. Serum concentration of VEGF is high in bronchial asthma and diabetes mellitus. VEGF's normal function is to create new blood vessels during embryonic development, new blood vessels after injury, muscle following exercise, and new vessels (collateral circulation) to bypass blocked vessels.

Anti-VEGF rAb Products

Creative Biolabs' anti-VEGF recombinant antibody products are meticulously developed using advanced genetic engineering techniques, ensuring high purity, lot-to-lot consistency, and exceptional specificity. These antibodies offer superior binding affinity and functional activity, making them ideal tools for a diverse array of applications, from fundamental research to preclinical drug development. Their recombinant nature guarantees a reliable and scalable supply, free from animal-derived contaminants.

Table 1. Featured anti-VEGF recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
TAB-298CQ Human Anti-VEGF Recombinant Antibody (TAB-298CQ) Human, Mouse Human IgG ELISA, Inhib
TAB-290CQ Anti-Human VEGF Recombinant Antibody (TAB-290CQ) Human Mouse ELISA, WB, Neut
PABC-131 Human Anti-VEGF Recombinant Antibody (clone B20-4) Human, Mouse Human IgG ELISA, Neut, Block
TAB-012-F(E) Anti-Human VEGF Recombinant Antibody Fab Fragment (TAB-012-F(E)) Human Humanized (from mouse) Fab - G1 - kappa IP, IF, FuncS, FC, Neut, ELISA, IHC
TAB-011 Anti-Human VEGF Recombinant Antibody (Bevacizumab) Human Humanized (from mouse) IgG1 - kappa FC, IP, ELISA, Neut, FuncS, IF, ICC

Creative Quality Control

At Creative Biolabs, the commitment to quality constitutes a fundamental principle, meticulously integrated across all phases of the production process. Rigorous quality control measures are systematically applied to all anti-VEGF recombinant antibody products, encompassing comprehensive characterization through advanced analytical techniques. Furthermore, each production lot undergoes exhaustive validation for purity, identity, potency, and endotoxin levels, thereby ensuring optimal performance and uncompromising safety for critical research applications.

Fig.1 ELISA analysis. (Creative Biolabs Original)Fig.1 ELISA analysis of anti-VEGF antibody
(Cat# TAB-298CQ, Creative Biolabs).

Fig.2 WB analysis. (Creative Biolabs Original)Fig.2 WB analysis of anti-VEGF antibody
(Cat# PABC-131, Creative Biolabs).

Fig.3 ELISA analysis. (Creative Biolabs Original)Fig.3 ELISA analysis of anti-VEGF antibody
(Cat# PABC-131, Creative Biolabs).

Fig.4 WB analysis. (Creative Biolabs Original)Fig.4 WB analysis of anti-VEGF antibody
(Cat# TAB-011, Creative Biolabs).

Fig.5 DB analysis. (Creative Biolabs Original)Fig.5 DB analysis of anti-VEGF antibody
(Cat# TAB-011, Creative Biolabs).

Fig.6 ELISA analysis. (Creative Biolabs Original)Fig.6 ELISA analysis of anti-VEGF antibody
(Cat# TAB-011, Creative Biolabs).

Customer Reviews

Excellent
Ma***i
Human Anti-VEGF Recombinant Antibody (HPAB-2817LY) (HPAB-2817LY)
The anti-VEGF recombinant antibody from Creative Biolabs proved instrumental in advancing our angiogenesis research. Its high specificity and consistent performance significantly optimized our experimental workflows, leading to considerable efficiencies.
28/May/2025
Excellent
Si***a
Recombinant Human Anti-VEGF Antibody (Fab-12) (PABX-185)
We've incorporated Creative Biolabs' anti-VEGF antibodies into our therapeutic development pipeline, and the results have been consistently reliable. The product's stability and activity are outstanding, making it an indispensable tool for our preclinical studies.
01/Jun/2025
Excellent
Ba***d
Human Anti-VEGF Recombinant Antibody (PABX-186) (PABX-186)
The technical support from Creative Biolabs was exceptional, guiding us through product selection and application. Their anti-VEGF recombinant antibody delivered precise and reproducible data, exceeding our expectations for our in vivo models.
15/Jun/2025

rAb Production

Creative Biolabs utilizes cutting-edge mammalian cell expression systems and advanced purification techniques to produce our anti-VEGF recombinant antibodies. This robust production platform ensures the generation of highly pure, functionally active antibodies with excellent batch-to-batch consistency. Our scalable manufacturing capabilities allow us to meet diverse project requirements, from small-scale research needs to large-scale therapeutic development.

Featured Anti-VEGF Recombinant Antibody Production PlatformsFig.7 Milligram-scale. (Creative Biolabs Original)
Fig.7 Milligram-scale anti-VEGF recombinant antibody production.

Fig.8 Gram-scale. (Creative Biolabs Original)Fig.8 Gram-scale anti-VEGF recombinant antibody production.

rAb Modalities

Our anti-VEGF recombinant antibody products are available in multiple modalities, including various isotype formats and conjugation options, providing unparalleled flexibility for diverse research and therapeutic applications.

Fig.9 VEGF antibody production and modalities. (Creative Biolabs Original)Fig.9 Full-length anti-VEGF recombinant antibody production and modalities.

VEGF-Targeted Drug Information

Table 2. Public drug targeting VEGF.

Company Research phase Classification Condition
Helvetic Bio (Helvetic BioPharma)
Helvetic BioPharma
STADA
Xbrane Biopharma (Originator)
Launched - 2023 Antibody-Derived Binding Proteins
Biosimilars
Follow-on Products
Humanized Monoclonal Antibodies
Age-related macular degeneration (AMD)
Choroidal neovascularization
Diabetic macular edema
Eye Disorders
Occlusion, retinal vein
Retinopathy, diabetic, proliferative
Retinopathy, vascular
Wet macular degeneration (exudative)
Celltrion (Originator)
Nippon Kayaku
Launched - 2022 Biosimilars
Cancer Immunotherapy
Follow-on Products
Humanized Monoclonal Antibodies
Cancer
Cancer, breast, metastatic
Cancer, cervix
Cancer, colorectal
Cancer, fallopian tube
Cancer, kidney (renal cell carcinoma), metastatic
Cancer, lung (non-small cell) (NSCLC) (adenocarcinoma)
Cancer, ovary (epithelial)
Cancer, solid tumor
Carcinoma, primary peritoneal (ovarian)
Genitourinary cancer
AffaMed Therapeutics
Biogen
Samsung Bioepis (Originator)
Launched - 2022 Antibody-Derived Binding Proteins
Follow-on Products
Humanized Monoclonal Antibodies
Age-related macular degeneration (AMD)
Choroidal neovascularization
Diabetic macular edema
Edema, macular
Retinopathy, diabetic, proliferative
Wet macular degeneration (exudative)
Bioeq IP
Coherus BioSciences
Formycon (Originator)
Sandoz
Teva
Launched - 2022 Antibody-Derived Binding Proteins
Biosimilars
Follow-on Products
Humanized Monoclonal Antibodies
Age-related macular degeneration (AMD)
Choroidal neovascularization
Diabetic macular edema
Eye Disorders
Occlusion, retinal vein
Retinopathy, diabetic
Retinopathy, diabetic, proliferative
Wet macular degeneration (exudative)
Chugai Pharmaceutical
Genentech (Originator)
Roche (Originator)
Launched - 2022 Bispecific Antibodies
Humanized Monoclonal Antibodies
Human Monoclonal Antibodies
Age-related macular degeneration (AMD)
Choroidal neovascularization
Diabetic macular edema
Occlusion, branch retinal vein
Occlusion, central retinal vein
Occlusion, retinal vein
Retinal diseases
Retinopathy, diabetic
Wet macular degeneration (exudative)
Gene Techno Science (Kidswell Bio)
Kidswell Bio (Originator)
Ocumension Therapeutics
Senju (Originator)
Launched - 2021 Antibody-Derived Binding Proteins
Follow-on Products
Humanized Monoclonal Antibodies
Choroidal neovascularization
Eye Disorders
Wet macular degeneration (exudative)
Luye Pharma (Originator)
Shandong Boan Biotech (Originator)
Launched - 2021 Cancer Immunotherapy
Follow-on Products
Humanized Monoclonal Antibodies
Cancer
Cancer, colorectal, metastatic
Cancer, liver (hepatocellular carcinoma)
Cancer, lung (non-small cell) (NSCLC)
Glioblastoma
Beijing Mabworks Biotech (Originator)
Betta Pharmaceuticals
Institute of Basic Medical Sciences AMMS (Originator)
Launched - 2021 Cancer Immunotherapy
Follow-on Products
Humanized Monoclonal Antibodies
Cancer
Cancer, colorectal, metastatic
Cancer, lung (non-small cell) (NSCLC)
Cancer, solid tumor
Cadila Pharmaceuticals (Originator) Launched - 2020 Cancer Immunotherapy
Follow-on Products
Humanized Monoclonal Antibodies
Cancer, breast
Cancer, cervix
Cancer, colorectal
Cancer, kidney
Cancer, lung
Cancer, ovary
Cancer, solid tumor
Glioblastoma multiforme
Coherus BioSciences
Innovent Biologics (Originator)
Launched - 2020 Cancer Immunotherapy
Follow-on Products
Humanized Monoclonal Antibodies
Cancer, colorectal, metastatic
Cancer, lung (non-small cell) (NSCLC)
Glioblastoma multiforme
3SBio
Merck & Co
Mundipharma
Samsung Bioepis (Originator)
Launched - 2020 Biosimilars
Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer, breast
Cancer, breast, metastatic
Cancer, cervix
Cancer, colorectal
Cancer, colorectal, metastatic
Cancer, fallopian tube
Cancer, kidney
Cancer, kidney (renal cell carcinoma)
Cancer, lung (non-small cell) (NSCLC)
Cancer, ovary (epithelial)
Cancer, solid tumor
Carcinoma, primary peritoneal (ovarian)
Unidentified condition
Dr Reddy's Laboratories (Originator) Launched - 2019 Cancer Immunotherapy
Follow-on Products
Humanized Monoclonal Antibodies
Cancer, breast, metastatic
Cancer, cervix
Cancer, colorectal, metastatic
Cancer, fallopian tube
Cancer, kidney (renal cell carcinoma), metastatic
Cancer, lung (non-small cell) (NSCLC)
Cancer, ovary (epithelial)
Cancer, solid tumor
Carcinoma, primary peritoneal (ovarian)
Glioblastoma

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

At Creative Biolabs, we are dedicated to supporting your scientific endeavors with high-quality reagents. Our anti-VEGF recombinant antibody products are a testament to our expertise and commitment to advancing biological research and drug discovery. To learn more about our offerings or to discuss your specific project needs, please do not hesitate to get in touch with us. Our expert team is ready to assist you.

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