BV421-DRB1*02:01/Human HLA-A (VGSDWRFLRGYHQYA) MHC Tetramer (CAT#: MHC-LC1069)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HLA-A-derived peptide of VGSDWRFLRGYHQYA covering 127-141 and DRB1*02:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
RNA Expression

Specifications

  • Allele
  • DRB1*02:01
  • Class
  • Class II
  • Antigen
  • HLA-A2
  • Antigen Species
  • Human
  • Peptide
  • VGSDWRFLRGYHQYA
  • Range
  • 127-141
  • Conjugate
  • BV421
  • Application
  • FCM

Target

  • Antigen Introduction
  • HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described.
  • Alternative Names
  • HLA-A; Major histocompatibility complex, class I, A; HLAA

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "HLA-A"

Immunotoxin

CAT Product Name Application Type
AGTO-L022F anti-HLA-A immunotoxin Fib75 (IgG)-α-sar Cytotoxicity assay, Functional assay

Recombinant Antibody

CAT Product Name Application Type
MOB-2307MZ Recombinant Mouse Anti-Human HLA-A Antibody (clone 9.M.208), Biotin-Conjugated FC, ICC/IF Mouse antibody
ZG-1014F Mouse Anti-HLA-A Antibody (clone BRA-23/9) FC, IHC-Fr Mouse IgG2a
ZG-1033F Mouse Anti-HLA-A Recombinant Antibody (clone HC10) ELISA, FC, IHC, ICC, IP, WB, Immuno-cryo-EM Mouse IgG2a
ZG-1034F Mouse Anti-HLA-A Recombinant Antibody (clone HCA2) ELISA, FC, IHC, ICC, IP, WB, Immuno-cryo-EM Mouse IgG1
VS3-FY676 Recombinant Rabbit Anti-HLA-A Antibody (clone R05-5H7) WB, IHC-Fr, IHC-P, ICC, IF, IP Rabbit IgG

Human Antibody

CAT Product Name Application Type
PABX-105 Recombinant Human Anti-HLA-A Antibody (T1) WB, ELISA, FuncS IgG
PABX-105-S (P) Recombinant Human Anti-HLA-A Antibody scFv Fragment (T1) WB, ELISA, FuncS scFv

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1617 Rabbit Anti-HLA-A Recombinant Antibody (clone DS1617AB) FC, ICC, IF, IHC-Fr, IHC-P, IP, WB Rabbit IgG

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for MHC-LC1069. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare