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HLA-A
HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008]
E*01:01/Human HLA-A leader 3-11 (VMAPRTLVL) MHC Tetramer (MHC-LC595)
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- Class: Class I
- Antigen: HLA-A leader 3-11
- Antigen Species: Human
- Peptide: VMAPRTLVL
- Conjugate: PE
E*01:03/Human HLA-A leader 3-11 (VMAPRTLVL) MHC Tetramer (MHC-LC594)
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- Class: Class I
- Antigen: HLA-A leader 3-11
- Antigen Species: Human
- Peptide: VMAPRTLVL
- Conjugate: PE
PE-DRB1*01:01/Human HLA-A (GSDARFLRGYHLYA) MHC Tetramer (MHC-LC1865)
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- Class: Class II
- Antigen: HLA-A*02:01
- Antigen Species: Human
- Peptide: GSDARFLRGYHLYA
- Conjugate: PE
E*01:01/Human HLA-A*02, A*24 leader (VMAPRTLVL) MHC Tetramer (MHC-LC666)
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- Class: Class I
- Antigen: HLA-A*02, A*24 leader
- Antigen Species: Human
- Peptide: VMAPRTLVL
- Conjugate: PE
E*01:03/Human HLA-A*02, A*24 leader R5K (VMAPKTLVL) MHC Tetramer (MHC-LC665)
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- Class: Class I
- Antigen: HLA-A*02, A*24 leader R5K
- Antigen Species: Human
- Peptide: VMAPKTLVL
- Conjugate: PE
E*01:03/Human HLA-A*02, A*24 leader (VMAPRTLVL) MHC Tetramer (MHC-LC664)
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- Class: Class I
- Antigen: HLA-A*02, A*24 leader
- Antigen Species: Human
- Peptide: VMAPRTLVL
- Conjugate: PE
E*01:01/Human HLA-A*02, A*24 leader R5K (VMAPKTLVL) MHC Tetramer (MHC-LC647)
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- Class: Class I
- Antigen: HLA-A*02, A*24 leader R5K
- Antigen Species: Human
- Peptide: VMAPKTLVL
- Conjugate: PE
E*01:03/Human HLA-A*02, A*24 leader R5K (VMAPKTLVL) MHC Tetramer (MHC-LC646)
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- Class: Class I
- Antigen: HLA-A*02, A*24 leader R5K
- Antigen Species: Human
- Peptide: VMAPKTLVL
- Conjugate: PE
APC-DRB1*02:01/Human HLA-A (VGSDWRFLRGYHQYA) MHC Tetramer (MHC-LC1068)
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- Class: Class II
- Antigen: HLA-A2
- Antigen Species: Human
- Peptide: VGSDWRFLRGYHQYA
- Conjugate: APC
PE-DRB1*02:01/Human HLA-A (VGSDWRFLRGYHQYA) MHC Tetramer (MHC-LC1067)
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- Class: Class II
- Antigen: HLA-A2
- Antigen Species: Human
- Peptide: VGSDWRFLRGYHQYA
- Conjugate: PE
BV421-DRB1*01:01/Human HLA-A (GSDARFLRGYHLYA) MHC Tetramer (MHC-LC1867)
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- Class: Class II
- Antigen: HLA-A*02:01
- Antigen Species: Human
- Peptide: GSDARFLRGYHLYA
- Conjugate: BV421
E*01:01/Human HLA-A*02, A*24 leader R5K (VMAPKTLVL) MHC Tetramer (MHC-LC667)
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- Class: Class I
- Antigen: HLA-A*02, A*24 leader R5K
- Antigen Species: Human
- Peptide: VMAPKTLVL
- Conjugate: PE
PE-H2-Kd/Human HLA-A (RYLENGKETL) MHC Tetramer (MHC-LC2631)
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- Class: Class I
- Antigen: HLA-A
- Antigen Species: Human
- Peptide: RYLENGKETL
- Conjugate: PE
PE-B*15:01/Human HLA-A (VGYVDDTQF) MHC Tetramer (MHC-LC4476)
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- Class: Class I
- Antigen: HLA-A
- Antigen Species: Human
- Peptide: VGYVDDTQF
- Conjugate: PE
PE-B*58:01/Human HLA-A (VGYVDDTQF) MHC Tetramer (MHC-LC4477)
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- Class: Class I
- Antigen: HLA-A
- Antigen Species: Human
- Peptide: VGYVDDTQF
- Conjugate: PE
PE-H2-Kd/Human HLA-A (RYLENGKETL) MHC Tetramer (MHC-LC4492)
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- Class: Class I
- Antigen: HLA-A
- Antigen Species: Human
- Peptide: RYLENGKETL
- Conjugate: PE
BV421-DRB1*02:01/Human HLA-A (VGSDWRFLRGYHQYA) MHC Tetramer (MHC-LC1069)
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- Class: Class II
- Antigen: HLA-A2
- Antigen Species: Human
- Peptide: VGSDWRFLRGYHQYA
- Conjugate: BV421
HLA-E*01:01/Human HLA-A (VMAPRTLVL) MHC Monomer (MHC-YF184)
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- Class: Class I
- Antigen: HLA-A
- Antigen Species: Human
- Peptide: VMAPRTLVL
- Conjugate: Biotin
APC-DRB1*01:01/Human HLA-A (GSDARFLRGYHLYA) MHC Tetramer (MHC-LC1866)
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- Class: Class II
- Antigen: HLA-A*02:01
- Antigen Species: Human
- Peptide: GSDARFLRGYHLYA
- Conjugate: APC
Recombinant Human Anti-human HLA-A Antibody scFv Fragment (MHH-500-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FuncS
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