Recombinant Anti-Human Lewis Y Antibody (Fc glycosylation) (CAT#: Gly-044LC)
This product is a humanized monoclonal antibody with N-glycosylation site Asn297 in the Fc region, and the glycosylated antibody shows at least 10 fold increased ADCC and at least 10 % reduced CDC activity. Antibody specifically binds human Lewis Y and can be potentially used in the treatment of breast cancer.
Specific Inquiry
Glyco-engineering
- Glycosylation site
- Asn297
- Glycosylation Type
- N-glycosylation
- Activity
- The antibody shows at least 10 fold increased ADCC and at least 10 % reduced CDC activity
Specifications
- Target
- Lewis Y (Lewis Y antigen)
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- IGN312 Glyco I
- Applications
- ELISA
Target
- Alternative Names
- Lewis Y; Lewis Y antigen; Lewis-Y; Lewis-Y antigen; Lewis(y) antigen; Lewis(y)
- Related Disease
- Breast cancer
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1634-VHH | Recombinant Anti-Human Lewis Y VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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