Human Anti-Lewis Y Recombinant Antibody (clone BR96) (CAT#: FAMAB-1327CQ)
This product is a recombinant human antibody that recognizes Lewis Y. The antibody was purified by affinity chromatography. It can be used in ELISA, IHC.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 ADCC and CDC assays with anti-Lewisy and Lewisb mAbs.
Anti-Lewisy and Lewisb mAbs, BR96 were screened by chromium release assay for ADCC with human PBMCs on Colo 205.
Noble, P., Spendlove, I., Harding, S., Parsons, T., & Durrant, L. G. (2013). Therapeutic targeting of Lewis y and Lewis b with a novel monoclonal antibody 692/29. PLoS One, 8(2), e54892.
Figure 2 Binding of BR96 LE to normal tissues.
BR96 was assessed for normal tissue binding by IHC. Normal staining to placenta are represented for BR96.
Noble, P., Spendlove, I., Harding, S., Parsons, T., & Durrant, L. G. (2013). Therapeutic targeting of Lewis y and Lewis b with a novel monoclonal antibody 692/29. PLoS One, 8(2), e54892.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Le(Y)
- Species Reactivity
- Human
- Clone
- BR96
- Applications
- IHC, Cyt
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Immunohistochemistry and Cytotoxicity.
Target
- Alternative Names
- Lewis Y; LeY
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Lewis Y"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1634-VHH | Recombinant Anti-Human Lewis Y VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for FAMAB-1327CQ. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IHC, ELISA, FC, WB, ADCC, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: FC, IHC, Cyt, FuncS
Application: ELISA, Inhib, FC, Neut
Application: ELISA, Block, WB, FC, IP
Application: ELISA, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.