Human Anti-Lewis Y Recombinant Antibody Hexamer (VS-0924-YC135), CDC Enhanced (CAT#: VS-0924-YC135)
Our product is a human anti-Lewis Y antibody hexamer with enhanced complement-dependent cytotoxicity (CDC) activity. This hexameric IgG1 targets the human Lewis Y antigen and includes mutations that enhance hexamerization. These mutations promote the formation of hexamers, which facilitate optimal C1q binding and thereby improve CDC.
Specific Inquiry
Specifications
- Host Species
- Human
- Type
- Antibody hexamer
- Specificity
- Human Lewis Y
- Species Reactivity
- Human
- Molecule Class
- ~ 900 kDa
- Applications
- CDC, ADCC, ELISA
- Conjugate
- None
- Related Disease
- LeY expressing tumors
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% determined as SDS-PAGE and SEC-HPLC
- Aggregation
- <5%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Lewis Y; Lewis Y antigen; Lewis-Y; Lewis-Y antigen; Lewis(y) antigen; Lewis(y)
- Long Name
- Lewis Y antigen
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1634-VHH | Recombinant Anti-Human Lewis Y VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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